Lange Instant Access: Acid-Base, Fluids, and Electrolytes / Edition 1

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Essential Evidence-Based Data for Common Clinical Encounters

"This is very useful for providers who desire a fast review of fluid, electrolyte, and acid-base disorders without asking for in-depth information. Background information about pathophysiology and references are not included, but are not needed. This makes the book unique and quite different from other available resources on the topic. 3 Stars."—Doody's Review Service

Make sense of acid-base and electrolytes with this compact, on-the-go guide—filled with clinical facts, figures, and data.

In this ultra-convenient resource, the authors have distilled down the most relevant insights from their acclaimed text Nephrology in 30 Days, giving you a complete, yet concise overview of acid-based and electrolytes—supported by evidence-based findings.

You'll find at-a-glance tables and a bulleted format that puts key diagnostic and clinical information right at your fingertips. This one-stop guide gets you up to speed on the major issues in acid-base and electrolyte disturbances, from metabolic acidosis to serum calcium disorders. It's the perfect clinical companion to more in-depth acid-base texts—one that goes beyond educational principles to focus on the real world of clinical medicine and patient management.

  • The perfect portable brain for the wards
  • Vital facts and figures everyone forgets to remember
  • Presented in easy-access tables
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Editorial Reviews

Doody's Review Service
Reviewer: Stefan G Kiessling, MD (University of Kentucky College of Medicine)
Description: This book, part of the Lange Instant Access series, provides a comprehensive and easily accessible guide for clinicians dealing with acid-base, fluid, and electrolyte problem-solving on a daily basis. Edited by experts in the field, this concise review of the facts in physiology and pathophysiology is presented in bullet format and tables useful as a quick reference for individuals familiar with the topics or for healthcare professionals trying to acquire a basic understanding without getting overwhelmed with information.
Purpose: The purpose is to provide a reference and easy to understand framework for the evaluation of commonly seen acid-base, fluid, and electrolyte abnormalities without going into as much detail as in medical textbooks. The book meets, and often exceeds, the objectives by providing a comprehensive tool that focuses on the core messages needed to properly assess patients in clinical practice.
Audience: The target audience includes medical providers at all levels (from student to senior faculty) taking care of patients with simple or complex disorders of acid-base, fluids, and electrolytes or anyone interested in an easy to access review of the (patho)physiology of the electrolyte homeostasis. It also appears to be a very useful resource for trainees in various subspecialties including intensive care medicine and nephrology. The authors are well known and published experts in the field.
Features: The book covers all common disorders of electrolyte, acid-base, and fluid homeostasis in a well organized fashion. Each chapter starts with a well structured outline allowing the readers to quickly find what they are looking for. Information is presented in a simple bullet (one sentence) format making it easy to review and digest. Additional information can be readily found in available textbooks if so desired.
Assessment: This is very useful for providers who desire a fast review of fluid, electrolyte, and acid-base disorders without asking for in-depth information. Background information about pathophysiology and references are not included, but are not needed. This makes the book unique and quite different from other available resources on the topic such as Halperin and Goldstein, Fluid, Electrolyte and Acid-Base Physiology: A Problem-Based Approach, 3rd edition (Elsevier, 1998) and Rose and Post, Clinical Physiology of Acid-Base Disorders, 5th edition (McGraw-Hill, 2000).
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Product Details

  • ISBN-13: 9780071486347
  • Publisher: McGraw-Hill Professional Publishing
  • Publication date: 6/15/2007
  • Series: LANGE Instant Access Series
  • Edition description: Book & Access card
  • Edition number: 1
  • Pages: 496
  • Sales rank: 998,289
  • Product dimensions: 4.50 (w) x 6.90 (h) x 0.72 (d)

Meet the Author

Robert F. Reilly, Jr., MD, holds the Frederick L. Coe Professorship in Nephrolithiasis Research in Mineral Metabolism and is Chief in the Section of Nephrology in the Veterans Affairs North Texas Health Care System; and Professor of Medicine in the Department of Medicine at the Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, The University of Texas Southwestern Medical Center at Dallas.

Mark A. Perazella, MD, FACP, is Associate Professor of Medicine, Director of the Renal Fellowship Program, and Director of Acute Dialysis Services in the Section of Nephrology, Department of Medicine, Yale University School of Medicine.

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Table of Contents

Chapter 1: Body Fluid Compartments and Intravenous Fluid Replacement, Robert F. Reilly, Jr., and Mark A. Perazella

1. Body fluid compartments
2. Intravenous solutions
3. General principles
4. Assessing extracellular fluid volume
5. Fluid resuscitation
6. Clinical examples of fluid resuscitation
Chapter 2: Disorders of Sodium Balance (Edema, Hypertension or Hypotension), Robert F. Reilly, Jr., and Mark A. Perazella
1. Introduction
2. Regulation of Na+ transport in kidney
3. Disorders associated with increased total body Na+ (ECF volume expansion)
4. Clinical manifestations of increased total body Na+ (ECF volume expansion)
5. General approach to the edematous patient
6. General treatment of the edematous patient
7. Clinical manifestations of decreased total body Na+ (ECF volume depletion)
8. General approach to the volume depleted patient
9. General Treatment of the Volume Depleted Patient
Chapter 3: Disorders of Water Balance (Hypo- and Hypernatremia), Robert F. Reilly, Jr., and Mark A. Perazella
1. Introduction
2. Hyponatremia
3. Etiology of hyponatremia
4. Signs and symptoms
5. Diagnosis
6. Treatment
7. Hypernatremia
8. Etiology
9. Signs and symptoms
10. Diagnosis
11. Treatment
Chapter 4: Diuretics, Mark A. Perazella
1. Introduction
2. Sites of diuretic action in kidney
3. Diuretic resistance
4. Clinical conditions associated with diuretic resistance
5. Treatment of diuretic resistance
Chapter 5: Disorders of K+ balance (Hypo- and Hyperkalemia), Mark A. Perazella
1. Introduction
2. K+ homeostasis
3. Role of K+ in the resting membrane potential
4. Cellular K+ distribution
5. K+ handling by the kidney
6. Factors controlling renal K+ excretion
7. Hypokalemia8. Etiology
9. Increased cellular K+ uptake
10. Increased renal K+ losses
11. Approach to the patient
12. Clinical manifestations
13. Treatment
14. Hyperkalemia
15. Etiology
16. Approach to the patient
17. Clinical manifestations
18. Treatment
Chapter 6: Metabolic Acidosis, Dinkar Kaw and Joseph I. Shapiro
1. Acid-Base Chemistry and Biology
2. The Bicarbonate Buffering System
3. Acid Excretion by the Kidney
4. Clinical Approach to the Patient with an Acid-Base Disorder
5. Pathophysiology, Compensation and Consequences
6. Use of the Serum and Urine Anion Gap in the Differential Diagnosis of Metabolic Acidosis
7. Differential Diagnosis of Metabolic Acidosis
8. Causes of Metabolic Acidosis
9. Treatment of Metabolic Acidosis
Chapter 7: Metabolic Alkalosis, Dinkar Kaw and Joseph I. Shapiro
1. Introduction
2. Maintenance of Metabolic Alkalosis
3. Clinical Features
4. Differential Diagnosis
5. Cl—Responsive and Cl—Resistant Causes of Metabolic Alkalosis
6. Treatment
Chapter 8: Respiratory and Mixed Acid-base Disturbances, Youngsook Yoon and Joseph I. Shapiro
1. Respiratory Disturbances
2. Respiratory Acidosis
3. Respiratory Alkalosis
4. Mixed Disturbances
Chapter 9: Disorders of Serum Calcium, Robert F. Reilly, Jr.
1. Regulation
2. Hypercalcemia
3. Hypocalcemia
Chapter 10: Disorders of Serum Phosphorus, Robert F. Reilly, Jr.
1. Regulation
2. Hyperphosphatemia
3. Hypophosphatemia
Chapter 11: Disorders of Serum Magnesium, Robert F. Reilly, Jr.
1. Introduction
2. Hypomagnesemia
3. Hypermagnesemia
Chapter 12: Appendix, Mark A. Perazella and Robert F. Reilly, Jr.
1. Introduction
2. Clinical assessment of glomerular filtration rate (GFR)
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