Lecture Notes: Clinical Pharmacology and Therapeutics / Edition 8

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Lecture Notes: Clinical Pharmacology and Therapeutics provides all the necessary information, within one short volume, to achieve a thorough understanding of how drugs work, their interaction with the body in health and disease, and how to use these drugs appropriately in clinical situations.

Presented in an easy-to-use format, this eighth edition builds on the clinical relevance for which the title has become well-known, and features an up-to-date review of drug use across all major clinical disciplines, together with an overview of contemporary medicines regulation and drug development.

Key features include:

  • A section devoted to the practical aspects of prescribing
  • Clinical scenarios and accompanying questions to contextualise information
  • End-of-chapter summary boxes
  • Numerous figures and tables which help distil the information for revision purposes

Whether you need to develop or refresh your knowledge of pharmacology, Lecture Notes: Clinical Pharmacology and Therpeutics presents 'need to know' information for those involved in prescribing drugs.

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Editorial Reviews

Doody's Review Service
Reviewer: Thomas L. Pazdernik, PhD (University of Kansas Medical Center)
Description: This eighth edition provides current updates to a resource on the clinical use of drugs that has become well known by practitioners of medicine in the United Kingdom and elsewhere over the last 30 years.
Purpose: From its inception, the overall aim of this book has been to describe with brevity and clarity the scientific background of rational prescribing while giving insight into practical aspects of therapeutics. Each edition has improved towards this ultimate goal. This latest edition again has made a significant step forward in achievement of the ultimate goal of the authors.
Audience: This book is more appropriate for practitioners of medicine than for the students who are learning about the use of drugs for the management of patients in their courses of study.
Features: The first of the book's three parts very concisely explains the principles of clinical pharmacology including pharmacokinetics, pharmacodynamics, and clinical trials. In 18 chapters, part 2 covers aspects of therapeutics, highlighting the drugs used in the management of specific diseases such as gastrointestinal disease, respiratory disease, cancer, etc. Most chapters have been significantly updated or rewritten and two new ones have been added on urological diseases and human immunodeficiency virus. Each chapter gives a clinical scenario usually followed by a key points box that identifies important aspects of diagnosing and managing diseases covered in the chapter. A few table and figures complement the text discussion. The eight chapters in part 3 discuss the practical aspects of prescribing drugs, dealing with topics such as individual dosing, prescribing for patients at the extreme ends of the age spectrum, use of drugs during pregnancy or breastfeeding, pharmacoeconomics, and drug poisonings. The last two chapters, "Drugs You Need in a Hurry" and "Prescribing and its Pitfalls" provide very useful information for practitioners.
Assessment: This is a very useful resource for practitioners, but would be less valuable for students learning about drugs during their training to become practitioners. The book is more valuable to a European than an American audience because of some differences in approved drugs and prescribing guidelines between the two countries.
From the Publisher

“The popularity of this Lecture Notes book merits an 8th edition publication.” (British Journal Global & Travel Health, 1 August 2013)

Clinical Pathology for the Veterinary Team will help experienced veterinary technicians set up various clinical laboratory diagnostic tests. It provides a good explanation of basic laboratory practices, the underlying concepts of many laboratory tests, and the physiology of common disease conditions. This book is well worth the price. (Journal of the American Veterinary Medical Association, December 2010) This book provides a good overall summary of basic clinical pathology in small animals. Although it is fairly short and concise, it contains all the necessary relevant information and includes a CD that takes readers thorough six complicated cases, step by step. This is a useful book that would be a handy reference to have in a practice. It is easy to read, concise, and informative. Although it is aimed at small animal veterinary teams, it includes limited information about large animal species, which is important for a good, general understanding. (Doodys, December 2010) Clinical Pathology for the Veterinary Team offers a fine recourse for technical team members involved in clinical diagnostic evaluation. Machinery calibration, normal anatomy, clinical diagnostics and more are revealed in chapters that provide key technical information for Obtaining and evaluating samples, surveying the disease process, the progress of identification and treatment, and including a DVD with interactive cases. Vet collections need this! (THE MIDWEST BOOK REVIEW, November 2010) Rosenfeld, a veterinarian who is associated with an education corporation that specializes in seminar training for the hospital team, and Dial (veterinary science and microbiology, U. of Arizona) provide a resource for technical veterinary team members performing clinical diagnostic evaluation in small animal lab work. (Book News, September 2010) ReviewUpdater-Profile_21@1326747466110

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Product Details

  • ISBN-13: 9781405197786
  • Publisher: Wiley
  • Publication date: 11/1/2010
  • Series: Lecture Notes Series, #17
  • Edition number: 8
  • Pages: 344
  • Product dimensions: 6.70 (w) x 9.50 (h) x 0.80 (d)

Meet the Author

Gerard A. McKay: Consultant Physician and Honorary Clinical Senior Lecturer, Glasgow Royal Infirmary

John L. Reid: Emeritus Professor of Medicine and Therapeutics, University of Glasgow

Matthew R. Walters: Professor of Clinical Pharmacology and Honorary Consultant Physician, Division of Cardiovascular and Medical Sciences, University of Glasgow

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Table of Contents

Contributors, iv

Preface, vi

Acknowledgements, vii

Part 1 Principles of Clinical Pharmacology

1 Pharmacodynamics and pharmacokinetics, 3

2 Clinical trials and drug development, 12

Part 2 Aspects of Therapeutics

3 Drugs and gastrointestinal disease, 21

4 Management of coronary artery disease and its complications, 33

5 Primary and secondary prevention of cardiovascular disease, 58

6 Drugs used to treat respiratory disease, 78

7 Drugs used to treat neurological disease, 89

8 Treatment of psychiatric disorders, 108

9 Antimicrobial therapy, 124

10 HIV and antiretroviral treatment, 148

11 Travel medicine and tropical disease, 160

12 Drugs and endocrine disease, 171

13 Drugs and the reproductive system, 190

14 Drugs and the urological system, 199

15 Cancer therapeutics, 205

16 Immunopharmacology, 217

17 Corticosteroids, 225

18 Drugs and the blood including anticoagulants and thrombolytic drugs, 229

19 Drugs and inflammatory joint disease, 244

20 Anaesthesia and the relief of pain, 254

Part 3 Practical Aspects of Prescribing

21 Clinical pharmacokinetics: dosage individualisation, 267

22 Influence of renal and hepatic disease on pharmacokinetics and pharmacodynamics, 273

23 Prescribing at extremes of age, 278

24 Drugs in pregnant and breastfeeding women, 282

25 Pharmacoeconomics: the economic evaluation of new drugs, 290

26 Poisoning and drug overdose, 297

27 Drugs you may need in a hurry, 313

28 Prescribing and its pitfalls, 318

Index, 326

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