Lipases: Their Structure, Biochemistry and Application

Overview

This 1994 book provides a fascinating account of the fast-moving field of lipase research. The contributions, written by active research workers, summarise developments in the field and give access to recent literature. It covers both the lipases proper (triglyceride lipases and the phospholipases. It gives a comprehensive picture of the state of knowledge of these enzymes, with a strong bias towards the fields that are attracting the greatest attention: their detailed molecular structure, their mechanism of ...

See more details below
Paperback (Reissue)
$49.25
BN.com price
(Save 12%)$56.00 List Price
Other sellers (Paperback)
  • All (4) from $41.98   
  • New (3) from $41.98   
  • Used (1) from $73.46   
Sending request ...

Overview

This 1994 book provides a fascinating account of the fast-moving field of lipase research. The contributions, written by active research workers, summarise developments in the field and give access to recent literature. It covers both the lipases proper (triglyceride lipases and the phospholipases. It gives a comprehensive picture of the state of knowledge of these enzymes, with a strong bias towards the fields that are attracting the greatest attention: their detailed molecular structure, their mechanism of action, their position in the evolution of enzymes, and their application both in the laboratory and industry. The book will continue to be of interest to those working in universities, in research institutes and in companies specialising in biotechnology. The book will also be a useful reference book for postgraduate students entering this field of research.

This book contains predominantly black-and-white illustrations, with some color illustrations.

Read More Show Less

Editorial Reviews

Anatoly Bezkorovainy
This book deals with a physiologically very important group of enzymes, the lipases. It includes the structure and evolution of lipases, their mechanisms of action, and their industrial and biotechnological uses. Each chapter is written by a different group of specialists in the field. The purpose is to bring an up-to-date summary of the ""fast-moving"" field of lipase biochemistry to the reader. There are few, if any, recent books available in this field, and for this reason, the authors' endeavor is of considerable value. The intended audience is researchers in the field of lipase biochemistry, graduate and postgraduate students aspiring to become lipase experts, and industrial biochemists who use lipases in their work. The level of writing is indeed appropriate to this audience. The book is well illustrated; some figures are in color. It attempts to establish some continuity in developing the narrative by starting with lipase evolution, proceeding through chemical and enzymatic properties of various classes of lipases, and ending with medical and industrial applications. A negative feature is the index, which is almost useless. The book is excellent as far as the structural chemistry and enzymology of lipases is concerned. However, it falls short on lipase physiology. Thus, phospholipases A2 and C are well described, but little if any mention is made of their role in the production of eicosanoids and cellular signaling. Mammalian intracellular lipases, e.g., hormone sensitive and acid lipase, are hardly mentioned. Nevertheless, this book is valuable, for it may pave the way for the appearance of more complete treatises on this very important group of enzymes.
Doody's Review Service
Reviewer: Anatoly Bezkorovainy, JD, PhD (Rush Medical College of Rush University)
Description: This book deals with a physiologically very important group of enzymes, the lipases. It includes the structure and evolution of lipases, their mechanisms of action, and their industrial and biotechnological uses. Each chapter is written by a different group of specialists in the field.
Purpose: The purpose is to bring an up-to-date summary of the "fast-moving" field of lipase biochemistry to the reader. There are few, if any, recent books available in this field, and for this reason, the authors' endeavor is of considerable value.
Audience: The intended audience is researchers in the field of lipase biochemistry, graduate and postgraduate students aspiring to become lipase experts, and industrial biochemists who use lipases in their work. The level of writing is indeed appropriate to this audience.
Features: The book is well illustrated; some figures are in color. It attempts to establish some continuity in developing the narrative by starting with lipase evolution, proceeding through chemical and enzymatic properties of various classes of lipases, and ending with medical and industrial applications. A negative feature is the index, which is almost useless.
Assessment: The book is excellent as far as the structural chemistry and enzymology of lipases is concerned. However, it falls short on lipase physiology. Thus, phospholipases A2 and C are well described, but little if any mention is made of their role in the production of eicosanoids and cellular signaling. Mammalian intracellular lipases, e.g., hormone sensitive and acid lipase, are hardly mentioned. Nevertheless, this book is valuable, for it may pave the way for the appearance of more complete treatises on this very important group of enzymes.

2 Stars from Doody
Read More Show Less

Product Details

  • ISBN-13: 9780521207997
  • Publisher: Cambridge University Press
  • Publication date: 1/26/2012
  • Edition description: Reissue
  • Pages: 382
  • Product dimensions: 5.98 (w) x 9.02 (h) x 0.79 (d)

Table of Contents

1. Sequence comparisons within the lipase family; 2. A sequence analysis of lipases, esterases and related proteins; 3. Lipases from plants; 4. Three-dimensional structures of two lipases from filamentous fungi; 5. Structural aspects of phospholipase C; 6. Phospholipase A2: mechanism and structure; 7. Structure and mechanism of human pancreatic lipase; 8. Kinetics of triglyceride lipases; 9. Gastric lipases: cellular, biochemical and kinetic aspects; 10. Lipase inhibitors; 11. Substrates for phospholipase C and sphigomyelinase; 12. Isolation and purification of lipases; 13. Industrial applications of lipases; 14. Lipases and phospholipases in organic synthesis; 15. Medical aspects of triglyceride lipases; 16. Protein engineering of lipases; Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)