Lipid Second Messengers

by Robert M. Bell, John H. Exton, Stephen M. Prescott

Overview

Lipids traditionally have been viewed as serving two functions: to form cellular membranes and to serve as energy stores. During the last two decades, a new role for lipids has taken center stage: lipids can act as signalling molecules. This book deals with a variety of lipids that have been shown to be messengers. Leading scientists explore all known lipid classes except steroid hormones. Researchers and educators in biochemistry as well as in molecular and cellular biology will appreciate this volume.

Product Details

ISBN-13:	9780306451744
Publisher:	Springer US
Publication date:	05/31/1996
Series:	Handbook of Lipid Research , #8
Edition description:	1996
Pages:	316
Product dimensions:	7.01(w) x 10.00(h) x 0.03(d)

Table of Contents

1: Diacylglycerols: Biosynthetic Intermediates and Lipid Second Messengers.- 2: Lipid Signaling for Protein Kinase C Activation.- 3: Phosphatidic Acid.- 4: PI 3-Kinase and Receptor-Linked Signal Transduction.- 5: Ceramide: A Novel Second Messenger and Lipid Mediator.- 6: Bioactive Properties of Sphingosine and Structurally Related Compounds.- 7: Platelet-Activating Factor and PAF-Like Mimetics.- 8: Lysophosphatidic Acid.- 9: Prostaglandins and Related Compounds: Lipid Messengers with Many Actions.

Editorial Reviews

Discusses a wide variety of complex lipids in cells that function either as intracellular or intercellular messengers, and the basic mechanisms of the signalling. Among them are phosphatidic and lyso-phosphatic acid, ceramide, sphingosine, platelet- activating factor and mimetics of it, prostaglandins and related compounds, and PI 3-kinase. Chapters also focus on biosynthetic intermediates, and signaling for protein kinase G activation. Of interest to biochemists, physiologists, pharmacologists, geneticists, and biologists. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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