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Doody's Review ServiceReviewer: Gene A. Homandberg, PhD (Rush Medical College of Rush University)
Description: This monograph presents sequencing data and sequencing problems and discusses the logic of sequencing. Both protein and DNA sequencing data are presented and discussed, with problems presented at the end of each chapter and in a separate chapter. This book is unique because of a chapter on the adventures in sequencing, a highly imaginative story about a CIA cryptanalyst who discovers that the Russians are using peptide sequence and restriction data to encode messages. The sequencing logic usedto decode the messages is presented in a dialog between two characters, in a highly imaginative and effective fashion.
Purpose: The purpose is to present the logic of protein and DNA sequencing and also to teach that the approach used in sequencing involves common logic.
Audience: The audience is meant to be structural biochemists with interests in sequencing. Molecular biologists will also find this book interesting. The audience should include students in biomedical sciences.
Features: The book's tables and line drawings are of sufficient quality; however, it should be noted that there are no illustrations for those with no background in sequencing. This book is aimed at individuals with some basic knowledge of the chemistry and data acquisition methods. Unfortunately, there are no literature references for these basics or for additional learning. However, the objectives are still very worthy, and the book is very successful in its stated purpose.
Assessment: This book has the unique objective of focusing on the logic of analyzing sequencing data, and it instills fun in this learning objective by including a chapter on adventures in sequencing. The combination of protein and DNA sequencing approaches is important, useful, and very effective. The problems are well thought out. This book is highly recommended for the library, bookstore, biochemist, and especially the graduate student.