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From The CriticsReviewer: Athanassios Argiris, MD(Northwestern University Feinberg School of Medicine)
Description: This book on the diagnosis and treatment of lung cancer is a part of the Methods in Molecular Medicine series.
Purpose: The main goal is to provide updates in methodologies useful in the diagnosis and treatment of lung cancer.
Audience: "Pursuant to the scope of the book most of the chapters have a narrow focus. The information provided is predominantly useful for the scientist with a particular interest in lung cancer. However, a few topics may be of interest to clinicians; for example, the utilization of TTF-1 expression in the diagnosis of lung cancer as well as the succinct overviews of surgical, radiation, and photodynamic therapies in lung cancer. "
Features: The book begins with overviews of the molecular and genetic abnormalities encountered in lung cancer. Subsequent chapters are devoted to techniques employed to analyze lung cancer specimens that spans topics from telomerase RNA expression to suppression subtraction hybridization, Southern blot analysis, DNA-based analysis, RT-PCR, and other methods. The clinical implication of each method is briefly discussed but detailed protocols for each technique are provided. The last part of the book includes reviews of the surgical management of lung cancer with a historical perspective, radiotherapy, photodynamic therapy, immunotherapy, and chemoprevention. Novel therapies, such as gene therapy, antisense technology, and tumor vaccines are discussed.
Assessment: This is a good compilation of scientific information on lung cancer. Although this work partially covers the extensive field of innovative methods and therapies that relate to cutting-edge lung cancer research and in many aspects lacks cohesiveness, it serves as a useful resource for scientists involved in lung cancer.