Overview

Lung cancer is a major cause of cancer-related deaths in men and women. However, since the first edition of Lung Cancer was published 14 years ago, rapid progress in the biology, prevention, diagnosis, and treatment of the disease has been made.

This outstanding team from the M.D. Anderson Cancer Center takes an evidence-based approach to lung cancer management and explains these advances in depth. Comprehensive treatment guidelines are provided, the third edition of Lung Cancer...

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Lung Cancer

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Overview

Lung cancer is a major cause of cancer-related deaths in men and women. However, since the first edition of Lung Cancer was published 14 years ago, rapid progress in the biology, prevention, diagnosis, and treatment of the disease has been made.

This outstanding team from the M.D. Anderson Cancer Center takes an evidence-based approach to lung cancer management and explains these advances in depth. Comprehensive treatment guidelines are provided, the third edition of Lung Cancer explores vital issues such as: Lung cancer susceptibility and risk assessment, The pathology and pathogenesis of peripheral lung adenocarcinoma including bronchioloalveolar carcinoma, Screening for early detection, Advances in molecular and genetic markers, The detection and treatment of pre-neoplastic lesions and screening for lung cancer, Novel therapies such as angiogenesis and multi-tyrosine kinase inhibitors. Lung Cancer is a concise summary of advances in lung cancer clinical research and treatment for the clinician and is an invaluable reference for respiratory physicians, medical oncologists, clinical and surgical oncologists.

The book contains predominantly black-and-white illustrations, with some color illustrations.

The second edition of this book is a concise and timely summary of recent advances and new research in the field of lung cancer emphasizing the biology, diagnosis, and treatment. It studies the factors influencing predisposition and the development of preneoplastic lesions, chemoprevention strategies, surgical methods, and current and future advances in radiation therapy. Editors consist of a surgeon, radiation oncologist and medical oncologist with contributions from an international list of 30 leading experts. New chapters to this edition include: Markers of Susceptibility, Three-Dimensional Conformal Radiotherapy, and Immunologic Approaches. New chapter covering thoracoscopy and its role in procedure and treatment. "...an excellent overview of a wide range of new developments in the clinical management and basic science of lung cancer. It should be essential reading for all practicing specialists in this field..." Review of the first edition from Thoracic Society News.

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Editorial Reviews

Gregory A. Masters
This book attempts to describe the important basic science and clinical aspects of lung cancer. This is done in a standard format with chapters on the biology, evaluation, management, and detection of lung cancer by a number of accomplished authors in the field. This book was originally published five years ago. The editors' goal is to provide a succinct summary of the recent advances, both in basic research and clinical management, of the widening field of lung cancer. The scope and management of lung cancer has evolved dramatically in the last five years and an up-to-date version of this text is welcome. This book appropriately subdivides these important areas of research with attention given to preneoplastic lesions, as well as advances in the preoperative evaluation, surgical management, radiation techniques, and new developments in chemotherapeutic agents for this disease. A significant portion is devoted to new methods of detection of lung cancer including molecular techniques and immunologic and biologic approaches. The target audience includes clinicians, basic researchers, and clinical researchers in the field of lung cancer. It certainly will be appropriate for specialists in surgical oncology, medical oncology, radiation oncology, and possibly pulmonary medicine. The editors are highly accomplished clinicians and researchers in the field of lung cancer. The book is well organized. It includes basic science research and then progresses through chapters dealing with different management techniques including surgery, radiation, chemotherapy, and combined modality therapy. The text is well written, but there is a relative paucity of pictures, drawings, and graphics. Thevarious graphs and tables included, many of which are reproductions of prior work, are effective in presenting relevant data. The information is quite up-to-date, as much as is possible for a textbook, with references from within approximately 18 months available for each chapter. This book provides a clear but very brief table of contents and lacks any subheadings. It is presented in a relatively easy-to-read format with an attractive cover and large type. The appendix gives adequate references to various topics in standard fashion. This is an excellent review of the relevant basic science and clinical topics in lung cancer and would be an appropriate choice for any medical or scientific library and/or bookstore. It would also be a good reference in an oncology office and perhaps appropriate for some clinicians who deal specifically with lung cancer including surgeons, radiotherapists, or medical oncologists as well as basic science researchers in the field of lung cancer. I believe that the subject areas incorporate the important major topics in lung cancer with a possible exception of adequate description of screening, imaging, and pathology sections. These are not individually represented in the text.
Booknews
A broad reference updated from the 1993 edition to include new developments but also to reflect the shift of emphasis in studies of the biology to factors influencing predisposition and the development of pre-neoplastic lesions. The topics include familiar predisposition, lung-sparing operations, surgery for small-cell lung cancer, three- dimensional conformal radiotherapy in bronchogenic carcinoma, new chemotherapeutic agents, chemoprevention, photodynamic therapy and thoracic malignancies, and genetic manipulations for treating lung cancer. Annotation c. by Book News, Inc., Portland, Or.
From The Critics
Reviewer: Joel C Seidman, MD(William Beaumont Hospitals)
Description: This is the third edition of a book that broadly addresses all aspects of lung cancer, including epidemiology, biology, and diagnosis, with special emphasis on recent advances in management occurring during the past decade. It is significantly revised from the first edition published 10-14 years earlier (in 1998, according to publisher's data; in 1994, according to the editors' preface). The compilation was edited by three well known academicians at the University of Texas M. D. Anderson Cancer Center — Jack A. Roth, MD, James D. Cox, MD, and Waun Ki Hong, MD), with over 60 contributors of international renown.
Purpose: In aggregate, an attempt is made to adopt the observations of authorities from diverse experience, providing a comprehensive review of the current state of the art on bronchogenic carcinoma.
Audience: "The audience would include primarily pulmonologists, thoracic surgeons, oncologists, or those aspiring to these disciplines. Others would undoubtedly find the reference selectively informative. It would additionally provide a real-life reference for basic science researchers in putting a face on applications carried out in the laboratory. "
Features: "The book covers the broad subject of bronchogenic carcinoma and augments substantially the presentation of the last edition. Although usually sufficient to carry out the ends of each chapter, the illustrations and graphics are quite limited and probably represent the most notable shortcoming of the book. The bibliographies at each chapter end are extensive and relevant. "
Assessment: "The is one of the most comprehensive and up-to-date treatises that I have surveyed, yet it is remarkably simple and to the point, covering basic molecular biology and genetics underlying the disease for the clinician, as well as epidemiology, early diagnosis, clinical presentation, and management. It focuses exceptionally upon the speculated growing role for targeted therapies with more limited toxicities than historical treatments. The book achieves its likely intended goals well. For an average practitioner, it comes across as very reachable, but probably not a compelling read. I would recommend the book highly to anyone in allied disciplines, and would personally consider it a practical resource to add to my personal library. "
From the Publisher

“The current edition builds on the strength of the previous editions … .Overall, the book was well planned. Each chapter is a concise review of the recent literature, with detailed references. Where warranted, there are tables, black-and-white diagrams, and photographs that expand on the information provided in the text. This well-organized book will be useful to pulmonologists, thoracic surgeons, radiation oncologists, medical oncologists, and others with an interest in lung cancer.” (New England Journal of Medicine, December 2008)

“One of the most comprehensive and up-to-date treatises that I have surveyed … .I would recommend the book highly to anyone in allied disciplines.” (Doody's Book Reviews)


3 Stars from Doody
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Product Details

  • ISBN-13: 9781444358667
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 8/26/2011
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 3
  • Pages: 480
  • Sales rank: 1,199,773
  • File size: 7 MB

Meet the Author

Jack A. Roth, MD FACS, Professor and Chairman, Bud Johnson Clinical Distinguished Chair, The University of Texas M.D. Anderson Cancer Center, Department of Thoracic & Cardiovascular Surgery and Professor of Molecular and Cellular Oncology, Director, W.M. Keck Center for Cancer Gene Therapy, Houston, Texas, USA.

James D. Cox, MD, Professor and Head, Division of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

Waun Ki Hong, MD, American Cancer Society Clinical Research Professor, Charles A. LeMistre Distinguished Chair in Thoracic Oncology and Professor and Chairman, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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Table of Contents

Preface
Contributors
1 Markers of Susceptibility 1
2 Biology of Preneoplastic Lesions 25
3 Familial Predisposition To Lung Cancer 57
4 Preoperative Evaluation of the Patient with Lung Cancer 73
5 Lung-Sparing Operations for Cancer 87
6 Role of Thoracoscopy in the Diagnosis and Treatment of Lung Cancer 105
7 Surgery for Small-Cell Lung Cancer 115
8 Extended Resections for Lung Cancer 135
9 High-Dose-Rate Remote Afterloading Endobronchial Brachytherapy 163
10 Three-Dimensional Conformal Radiotherapy in Bronchogenic Carcinoma 181
11 Combinations of Radiation Therapy and Chemotherapy for NSCLC 195
12 Preoperative and Postoperative Adjunctive Therapy for Resectable NSCLC 207
13 New Chemotherapeutic Agents in NSCLC 217
14 Chemoprevention 235
15 Molecular Detection of Lung Cancer 253
16 Fluorescence Detection 269
17 Photodynamic Therapy and Thoracic Malignancies 287
18 Growth-Factor Receptors as a Target for Therapy 309
19 Immunologic and Biologic Approaches to Lung Cancer Therapy 343
20 Genetic Manipulations for the Treatment of Lung Cancer 369
Index 383
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