Lung Function: Physiology, Measurement and Application in Medicine / Edition 6

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  • The only text to cover lung function assessment from first principles including methodology, reference values and interpretation
  • New for this edition:
    - More illustrations to convey concepts clearly to the busy physician

    - Text completely re-written in a contemporary style: includes user-friendly equations and more diagrams

    - New material covering the latest advances in the treatment of lung function, including more on sleep-related disorders, a stronger clinical and practical bias and more on new techniques and equipment

    - Uses the standard Vancouver referencing system

  • What the experts say:

    "I have always considered Dr Cotes' book the most authoritative book published on lung function. It is also the most comprehensive. “
    Dr Robert Crapo, Pulmonary Division, LDS Hospital, Salt Lake City, USA

    “I think I can fairly speak on behalf of staff in lung function departments the length and breadth of the country - that a sixth edition of Cotes would be gratefully received."
    Dr Brendan Cooper, Clinical Respiratory Scientist, Nottingham City Hospital

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Editorial Reviews

From the Publisher
"I have always considered Dr Cotes' book the most authoritative book published on lung function. It is also the most comprehensive. I strongly support a sixth edition."
Dr Robert Crapo, Pulmonary Division, LDS Hospital, Salt Lake City, USA

"I am delighted as chairman of the ARTP to consider the proposal for a sixth edition of John Cotes' book. I think without exception every lung function laboratory will have an earlier copy of the book (indeed I am the proud owner of the first edition myself!). I felt that the fifth edition was a marked improvement on earlier versions, particularly with respect to the layout, as well as the updated content. To update the content further and to involve more authors, but maintaining John's direction, will product a valuable update to the book.
"I hope my comment will help you to reach a positive decision...I think I can fairly speak on behalf of staff in lung function departments the length and breadth of the country - that a sixth edition of Cotes would be gratefully received."
Dr Brendan Cooper, Clinical Respiratory Scientist, Nottingham City Hospital

"The proposed new edition will be a revitalised version of a familiar and respected text...The primary author is obviously still enthusiastic and energetic enough to complete the project but has sensibly taken on collaborators to refresh the style and widen the perspective...The book is likely to have the advantage over its competitors in terms of existing stature. Also it does provide a role as a reference text for laboratories and departments."
Dr Michael Morgan, Consultant Physician, Department of Respiratory medicine, Glenfield Hospital, Leicester

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Product Details

  • ISBN-13: 9780632064939
  • Publisher: Wiley
  • Publication date: 4/28/2006
  • Edition description: REV
  • Edition number: 6
  • Pages: 648
  • Product dimensions: 8.95 (w) x 11.20 (h) x 1.52 (d)

Meet the Author

John E Cotes, Visitor, University Department of Physiological Sciences, Formerly Reader in Respiratory Physiology, External Scientific Staff of Medical Research Council, and Honorary Consultant in Clinical Respiratory Physiology, Newcastle upon Tyne, UK

David J Chinn, Senior Research Fellow in Epidemiology, Centre for Primary and Community Care, University of Sunderland, Sunderland, UK

Martin R Miller, Consultant Physician, University Hospital Birmingham NHS Trust, Birmingham, UK

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Table of Contents




Part 1. Foundations.

1. Early Developments and Future Prospects.

2. Getting Started.

3. Development and Functional Anatomy of the Respiratory System.

4. Body Size and Anthropometric Measurements.

5. Numerical Interpretation of Physiological Variables.

6. Basic Terminology and Gas Laws.

7. Basic Equipment and Measurement Techniques.

8. Respiratory Surveys.

Part 2. Physiology and Measurement of Lung Function.

9. Thoracic Cage and Respiratory Muscles.

10. Lung Volumes.

11. Lung and Chest Wall Elasticity.

12. Forced Ventilatory Volumes and Flows (Ventilatory Capacity).

13. Determinants of Maximal Flows (Flow Limitation).

14. Theory and Measurement of Respiratory Resistance (Including Whole Body Plethysmography).

15. Control of Airway Calibre and Assessment of Changes.

16. Distribution of Ventilation.

17. Distribution and Measurement of Pulmonary Blood Flow.

18. Inter-relations Between Lung Ventilation and Perfusion.

19. Transfer of Gases into Blood in Alveolar Capillaries.

20. Transfer Factor (Diffusing Capacity) for Carbon Monoxide and Nitric Oxide.

21. The Oxygenation of Blood.

22. Gas Exchange for Carbon Dioxide and Acid-Base Balance.

23. Control of Respiration.

24. Newborn Babies, Infants and Young Children (Ages 0–6 years).

Part 3. Normal Variation in Lung Function.

25. Normal Lung Function from Childhood to Old Age.

26. Reference Values for Lung Function in White (Caucasian) Children and Adults.

27. Genetic Diversity: Reference Values in non-Caucasians.

Part 4. Exercise.

28. Physiology of Exercise and Changes Resulting from Lung Disease.

29. Exercise Testing and Interpretation, including Reference Values.

30. Assessment of Exercise Limitation, Disability and Residual Ability.

31. Exercise in Children.

Part 5. Breathing During Sleep.

32. Investigation and Physiology of Breathing During Sleep.

33. Assessment and Treatment of Sleep Related Breathing Disorders.

Part 6. Potentially Adverse Environments.

34. Hypobaria: High Altitude and Aviation Physiology and Medicine.

35. Immersion in Water, Hyperbaria and Hyperoxia Including Oxygen Therapy.

36. Cold, Heat and the Lungs.

37. Airborne Respiratory Hazards: Features, Protective Mechanisms and Consequences.

Part 7. Lung Function in Clinical Practice.

38. Patterns of Abnormal Function in Lung Disease.

39. Strategies For Assessment.

40. Lung Function in Asthma, COPD, Emphysema and Diffuse Lung Fibrosis.

41. How Individual Diseases Affect Lung Function (Compendium).

42. Lung Function in Relation to General Anaesthesia and Artificial Ventilation.

43. Lung Function in Relation to Surgery.

44. Pulmonary Rehabilitation.


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