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Doody's Review ServiceReviewer: Eugene A Davidson, PhD (Georgetown University School of Medicine)
Description: It has long been accepted that lupus (systemic lupus erythematosus) has the hallmarks of an autoimmune disease. As the knowledge base regarding this disease has broadened, factors relating to genotype and possible external triggers have become better appreciated.
Purpose: This volume represents a comprehensive review of current information on lupus.
Audience: The intended audience is anyone who works in the field of lupus.
Features: Basic concepts of autoimmunity are covered as they relate to tissue damage, disease pathology, and many issues relating to host responses. Each is accompanied by a detailed bibliography and the volume as a whole has a useful index.
Assessment: This effort represents a comprehensive and authoritative coverage of work on lupus. It is up to date in that the latest developments in the field are provided (e.g., the role of Fas and apoptosis in disease management). All workers in this area will find this a valuable resource. It also represents a worthwhile addition to medical libraries.