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Management of Acute Kidney Problems / Edition 1

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Overview

Acute kidney failure is an important clinical area in the intensive care unit setting. An estimated 5–20% of critically ill patients experience an episode of acute kidney failure during the course of their illness, and about 5% of patients admitted to an ICU will eventually require renal replacement therapy. In these patients, in-hospital mortality is extremely high, exceeding 50%. Thus, the early detection and causal treatment of acute kidney problems is vitally important for a successful outcome. Written by internationally renowned experts, this clinical reference offers helpful advice with the most recent information on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney failure as a fundamental prerequisite for prevention of this disorder. Moreover, it also covers differential diagnostic approaches for patients with acute renal failure and provides a detailed outline of important measures for their clinical management. Finally, separate chapters are dedicated to various key aspects related to the adequate delivery of acute renal replacement therapy. It is intended as a helpful guide for all clinicians involved in the care of patients at risk of developing acute kidney problems.

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Editorial Reviews

Doody Reviews
Reviewer: Jon Webb, MD (University of Kentucky College of Medicine)
Description: This is an up-to-date book on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney injury.
Purpose: It is intended for clinicians who frequently encounter patients with acute kidney disease. With an emphasis on intensive care unit patients, the 104 contributors bring international expertise in diagnostic approaches to acute kidney disease as well as measures for clinical management. The later sections detail specific disorders related to acute kidney disease, and concluding chapters focus on aspects of delivering acute renal replacement therapy.
Audience: This is a helpful resource for physicians practicing in the intensive care unit setting. From internists to critical care specialists, this book provides a starting point for clinical management. The more specialized sections are oriented towards the care provided by nephrologists.
Features: The 63 chapters are grouped into eight main sections. The first five focus on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney injury. The sixth section discusses specific entities associated with acute kidney failure, and the seventh details delivery of acute renal replacement therapy. The final section explores nonrenal indications for extracorporeal therapies. Multiple colorful tables and figures enhance the text. Short reviews in the form of core messages and clinical pearls provide a rapid and informative summary of key learning points
Assessment: This book provides a concise starting point for managing patients with acute kidney failure and attempts to cover an enormous variety of information. In the process, certain chapters provide such a concise review that guidance on clinical management is limited. However, the editors describe the book as an initial reference likely leading to further reading. In this regard, the extensive lists of references following each chapter are an excellent resource. In our expanding body of literature, access to the Internet has provided an invaluable resource for the latest advances in healthcare. Thus, books can be quickly outdated, and many have begun to incorporate an online edition to maintain relevancy. This book does not include access to an online version, but it excels at detailing core learning points. Whether using it as a quick guide to clinical management or in preparation for an examination, this book is very helpful. I would recommend it in particular for those in training for critical care medicine or nephrology, and as a solid resource for those with frequent exposure to patients with acute kidney disease.
Doody's Review Service
Reviewer: Jon Webb, MD (University of Kentucky College of Medicine)
Description: This is an up-to-date book on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney injury.
Purpose: It is intended for clinicians who frequently encounter patients with acute kidney disease. With an emphasis on intensive care unit patients, the 104 contributors bring international expertise in diagnostic approaches to acute kidney disease as well as measures for clinical management. The later sections detail specific disorders related to acute kidney disease, and concluding chapters focus on aspects of delivering acute renal replacement therapy.
Audience: This is a helpful resource for physicians practicing in the intensive care unit setting. From internists to critical care specialists, this book provides a starting point for clinical management. The more specialized sections are oriented towards the care provided by nephrologists.
Features: The 63 chapters are grouped into eight main sections. The first five focus on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney injury. The sixth section discusses specific entities associated with acute kidney failure, and the seventh details delivery of acute renal replacement therapy. The final section explores nonrenal indications for extracorporeal therapies. Multiple colorful tables and figures enhance the text. Short reviews in the form of core messages and clinical pearls provide a rapid and informative summary of key learning points
Assessment: This book provides a concise starting point for managing patients with acute kidney failure and attempts to cover an enormous variety of information. In the process, certain chapters provide such a concise review that guidance on clinical management is limited. However, the editors describe the book as an initial reference likely leading to further reading. In this regard, the extensive lists of references following each chapter are an excellent resource. In our expanding body of literature, access to the Internet has provided an invaluable resource for the latest advances in healthcare. Thus, books can be quickly outdated, and many have begun to incorporate an online edition to maintain relevancy. This book does not include access to an online version, but it excels at detailing core learning points. Whether using it as a quick guide to clinical management or in preparation for an examination, this book is very helpful. I would recommend it in particular for those in training for critical care medicine or nephrology, and as a solid resource for those with frequent exposure to patients with acute kidney disease.
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Product Details

  • ISBN-13: 9783540694137
  • Publisher: Springer Berlin Heidelberg
  • Publication date: 2/19/2010
  • Edition description: 2010
  • Edition number: 1
  • Pages: 678
  • Product dimensions: 8.00 (w) x 10.40 (h) x 1.30 (d)

Table of Contents

A. General Considerations

1. Introduction

2. Definition and Classification of Acute Kidney Failure

3. Overview of Pathophysiology, Etiology and Epidemiology

3.1. Mechanisms of Kidney Injury and Repair

3.2. Uremic Toxins

3.2. Pre-renal Acute Kidney Failure

3.3. Intrinsic Acute Kidney Failure

3.4. Urinary Tract Obstruction

3.5. Epidemiology and Economical Impact

4. Diagnostic Evaluation and Procedures

4.1. Clinical Evaluation

4.2. Laboratory Investigation

4.3. Kidney Function Tests and Urinalysis

4.4. Radiography

4.5. Ultrasonography

4.6. Kidney biopsy

5. Prevention and Conservative Therapy of Acute Kidney Failure

5.1. Volume Resuscitation and Management

5.1. Electrolyte Homeostasis

5.3. Acid-Base Balance

5.2. Monitoring and Management of Systemic Hemodynamics

5.3. Correction of Anaemia

5.4. Nutrition and Metabolism

5.5. Glucose and Insulin

5.6. Bleeding and Hemostasis

5.7. Neurological Problems

5.8. Gastrointestinal Complications

5.9. Cardiovascular Complications

5.10. Specific Interventions / Drugs

6. Indications to Start Kidney Replacement Therapy

7. Long-term Outcome of Acute Kidney Failure

B. Diagnosis and Management of Specific Disorders

1. Acute Kidney Failure in Sepsis

2. Cardiogenic Shock and Acute Kidney Failure

3. Acute Kidney Problems in Congestive Heart Failure

4. Hepato-Renal Syndrome

5. ARDS and Kidney Failure

6. Toxic Nephropathy due to Drugs and Poisons

7. Toxic Nephropathy due to Radio Contrast Media

8. Acute Glomerulonephritis, Vascultis, and Pulmo-Renal Syndromes

9. Hemolytic Uremic Syndrome / Thrombotic Thrombocytopenic Purpura

10. Acute Interstitial Nephritis

11. Myoglobinuric Acute Kidney Failure

12. Tropical Infections and Acute Kidney Failure

13. AIDS and Acute Kidney Failure

14. Acute Kidney Failure in Hematological Disorders and Tumor Lysis Syndrome

15. Acute Kidney Failure follwing Cardiovascular Surgery

16. Polytrauma and Acute Kidney Failure

17. Burns and Acute Kidney Failure

18. Acute Kidney Transplant Failure

19. Acute Kidney Failure during Pregnancy and Post Partum

20. Acute Kidney Failure in Children

C. Temporary Replacement of Kidney Function

1. Principles of Extracorporeal Blood Purification: Hemodialysis, Hemofiltration, Hemodiafiltration

2. Membranes for Dialysis and Hemofiltration

3. Dialysates and Substitution Fluids

4. Intermittent Hemodialysis

5. Continuous Renal Replacement Therapies

6. SLEDD and SCUF

7. Quantifying the Dose of Acute Kidney Replacement Therapy

7. Adequacy and Dosing of Acute Kidney Replacement Therapy

8. Anticoagulation for Acute Dialysis

9. Vascular Access for Acute Dialysis

10. Principles and Practice of Acute Peritoneal Dialysis

11. Choosing a Therapy Modality for Acute Kidney Replacement Therapy

12. Stopping Acute Kidney Replacement Therapy

D. Management of Specific Issues

1. Anaesthesia in Patients with Acute Kidney Failure

2. Drug Dosing in Acute Kidney Failure and During Kidney Replacement Therapy

3. Acute Kidney Replacement Therapy In Children

4. Extracorporeal Therapies for Non-Renal Indications

4.1. Extracorporeal Therapies and Immunomodulation During Sepsis

4.2. Extracorporeal Liver Support

4.3. Extracorporeal Removal of Drugs and Toxins

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