Manual of Clinical Hematology / Edition 3

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Overview

Completely revised for its Third Edition, this Spiral(R) Manual is a practical quick-reference guide for the diagnosis and treatment of diseases of the blood. Coverage includes leukemias, disorders of lymph nodes, bleeding disorders, anemias, and platelet disorders. The book is organized by disease type, with several chapters broken down into discussions of specific disorders. Concise and easy-to-read descriptions of each disease provide clinical recommendations and essential pathophysiological information. This edition includes a new chapter on allogeneic and autologous bone marrow transplantation procedures for hematologic malignancies. All other chapters have been extensively revised and updated.

Appropriate for: Fourth Year Medical Students, House Officers.

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Editorial Reviews

Doody's Review Service
Reviewer: Anaadriana Zakarija, MD (Northwestern University Feinberg School of Medicine)
Description: This is a comprehensive and practical overview of clinical hematology. The previous edition was published in 1995.
Purpose: The purpose is to provide an overview of common clinical hematologic conditions, both benign and malignant. There is a definite need for a good, concise portable manual. The editor and authors have succeeded in this.
Audience: According to the author, this book is geared primarily toward students and housestaff., but the manual's detail and content make it useful for an even broader audience. Internists and family physicians can use this book to update their knowledge of this rapidly changing field and answer clinical questions encountered in daily practice. It is a good reference even for physicians doing subspecialty training in hematology. The references at the end of each chapter provide good direction for further reading. Most references are primary sources, original journal articles.
Features: The manual covers both benign and malignant conditions in hematology. Disorders of each of the hematopoetic cell lines are reviewed. Most topics are introduced with a review of the basic pathophysiology and biochemistry, which is quite detailed. Clinical presentations, diagnostic methods, and treatment options are discussed. Chapters on leukemia include the most recent updated classifications. Hemostasis and coagulation is not forgotten. There is also a detailed chapter on transfusion medicine, which is very practical. New to this edition is a basic introduction to bone marrow transplantation. Important information is summarized well in tables. Most chapters include figures and tables. The one feature this book lacks is a color atlas. Just a few photographs would be necessary to round out an otherwise excellent resource.
Assessment: It is quite a task to put together a comprehensive manual of hematology in a spiral bound format that is portable. This book accomplishes that quite well. The new edition includes updates from discoveries at the molecular/genetic level to summaries of everchanging advances in treatment. This manual is a valuable resource for physicians at all levels. It can be a good introduction to the field or a concentrated review.
From The Critics
Reviewer: Anaadriana Zakarija, MD(Northwestern University Feinberg School of Medicine)
Description: This is a comprehensive and practical overview of clinical hematology. The previous edition was published in 1995.
Purpose: "The purpose is to provide an overview of common clinical hematologic conditions, both benign and malignant. There is a definite need for a good, concise portable manual. The editor and authors have succeeded in this. "
Audience: According to the author, this book is geared primarily toward students and housestaff., but the manual's detail and content make it useful for an even broader audience. Internists and family physicians can use this book to update their knowledge of this rapidly changing field and answer clinical questions encountered in daily practice. It is a good reference even for physicians doing subspecialty training in hematology. The references at the end of each chapter provide good direction for further reading. Most references are primary sources, original journal articles.
Features: "The manual covers both benign and malignant conditions in hematology. Disorders of each of the hematopoetic cell lines are reviewed. Most topics are introduced with a review of the basic pathophysiology and biochemistry, which is quite detailed. Clinical presentations, diagnostic methods, and treatment options are discussed. Chapters on leukemia include the most recent updated classifications. Hemostasis and coagulation is not forgotten. There is also a detailed chapter on transfusion medicine, which is very practical. New to this edition is a basic introduction to bone marrow transplantation. Important information is summarized well in tables. Most chapters include figures and tables. The one feature this book lacks is a color atlas. Just a few photographs would be necessary to round out an otherwise excellent resource. "
Assessment: "It is quite a task to put together a comprehensive manual of hematology in a spiral bound format that is portable. This book accomplishes that quite well. The new edition includes updates from discoveries at the molecular/genetic level to summaries of everchanging advances in treatment. This manual is a valuable resource for physicians at all levels. It can be a good introduction to the field or a concentrated review. "
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Product Details

Table of Contents

Contributing Authors
Preface
1 Hematopoiesis and Hematopoietic Growth Factors 1
2 The Anemias 17
Iron-Deficiency Anemia 17
Megaloblastic Anemia 38
Anemia of Chronic Disease 53
Aplastic Anemia 60
3 Primary and Secondary Erythrocytosis 70
4 Hemolytic Anemia: Congenital and Acquired 87
5 Iron-Overload Disorders 115
6 Abnormalities of Hemoglobin 146
7 Disorders of Granulocytes: Qualitative and Quantitative 163
8 Platelet Disorders: Hereditary and Acquired 190
9 Myeloproliferative Diseases 204
10 Myelodysplastic and Preleukemic Syndromes 210
11 Acute Leukemias in Adults 222
12 Chronic Leukemia 236
Chronic Lymphocytic Leukemia and Related Disorders 236
Chronic Myelogenous Leukemia 242
13 Multiple Myeloma and Related Monoclonal Gammopathies 251
14 Benign Lymphocyte Disorders 277
15 Malignant Lymphomas 294
Hodgkin's Disease 294
Non-Hodgkin's Lymphomas 316
Cutaneous T-Cell Lymphomas 330
16 Hemostasis: Hemorrhagic and Thrombotic Disorders 349
17 Transfusion: Blood and Blood Components 380
18 Hematologic Aspects of Human Immunodeficiency Virus Infection 402
App. A Normal Hematologic Parameters 411
App. B Bone Marrow Differential Counts During Infancy and Childhood 416
App. C Complement Activation 418
App. D Schilling Test: Interpretation of Excretion Values 419
App. E Hemoglobin-Oxygen Equilibrium Curve 420
App. F Osmotic Fragility of Erythrocytes 421
App. G Transitions in Myeloproliferative Disorders 424
App. H FAB Classifications 425
App. I Cytochemical Reactions in Normal and Abnormal Blood Cells 427
App. J Cytochemical Reactions: Esterase 429
App. K Cytochemical Reactions in the Acute Leukemias FAB Classification 430
App. L Platelet Organelles and Constituents 431
App. M Pathways of Blood Coagulation 432
App. N Coagulation Schema as Previously Conceived 433
App. O Summary of Blood Components 434
App. P Nomograms for Determining Body Surface Area 439
App. Q Growth Factors and Hematopoietic Differentiation 441
Index 443
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