Manual of Clinical Microbiology / Edition 7

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In 1970, the first edition of the Manual of Clinical Microbiology (MCM) was published by the American Society for Microbiology. Nineteen editors and 98 authors presented, in 77 chapters and 727 pages of text, a state-of-the-art description of clinical microbiology...The Manual has now expanded to 130 chapters and 1,773 pages of text. Despite the many changes in clinical microbiology, the fundamental philosophy of the Manual has remained the same...The Manual "is intended to guide clinical microbiologists in the selection, performance, and interpretation of laboratory procedures for diagnostic and therapeutic applications. It is a reference source defining not only what is done in clincial microbiology laboratories but also what these activities signify."...With many changes in editors, authors, subject matter, and presentation, we believe that we have maintained the tradition of the Manual of Clinical Microbiology and improved from the foundation of the last six editions. We hope that the readership will find this text useful, accurate, and timely.

Provides all microbiologists, laboratorians, and infectious disease professionals with the definitive reference work for running an effective diagnostic laboratory. Guides the clinical microbiologist in the selection, performance, and interpretation of laboratory procedures. Focuses on the when and why of diagnostic procedures, as well as the how. Presents a direct approach to organizing information with thorough but concise treatments of all the major areas of microbiology, including new microbial discoveries, changing diagnostic methods, and emerging therapeutic challenges facing clinicians.

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Editorial Reviews

A reference for clinical microbiologists, pathologists, clinicians, and students. Coverage includes general issues in clinical microbiology, the clinical microbiology lab in infection control and prevention, diagnostic technologies in clinical microbiology, bacteriology, virology, mycology, parasitology, antimicrobial agents and susceptibility testing, and reagents, stains, and media. This edition is enhanced by perspectives from editors and authors outside the US. Some material is consolidated and reorganized. Murray teaches in the departments of pathology and medicine at the Washington University School of Medicine. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9781555811266
  • Publisher: ASM Press
  • Publication date: 5/28/1999
  • Edition description: Older Edition
  • Edition number: 7
  • Pages: 1773
  • Product dimensions: 8.71 (w) x 11.21 (h) x 2.50 (d)

Table of Contents

Editorial Board
Sect. I General Issues in Clinical Microbiology 1
1 Introduction to the Seventh Edition of the Manual of Clinical Microbiology 3
2 Laboratory Management 4
3 Commensal and Pathogenic Microorganisms of Humans 23
4 Specimen Collection, Transport, and Storage 33
5 Specimen Processing 64
Sect. II The Clinical Microbiology Laboratory in Infection Control and Prevention 105
6 Infection Control Epidemiology and Clinical Microbiology 107
7 Laboratory Procedures for the Epidemiologic Analysis of Microorganisms 116
8 Decontamination, Disinfection, and Sterilization 138
9 Prevention and Control of Laboratory-Acquired Infections 165
10 Investigation of Foodborne and Waterborne Disease Outbreaks 174
Sect. III Diagnostic Technologies in Clinical Microbiology 191
11 Manual and Automated Systems for Microbial Identification 193
12 Immunoassays for the Diagnosis of Infectious Diseases 202
13 Molecular Detection and Identification of Microorganisms 215
Sect. IV Bacteriology 246
14 Taxonomy and Classification of Bacteria 249
15 Algorithm for Identification of Aerobic Gram-Positive Cocci 262
16 Staphylococcus and Micrococcus 264
17 Streptococcus 283
18 Enterococcus 297
19 Leuconostoc, Pediococcus, Stomatococcus, and Miscellaneous Gram-Positive Cocci That Grow Aerobically 306
20 Algorithm for Identification of Aerobic Gram-Positive Rods 316
21 Coryneform Gram-Positive Rods 319
22 Listeria, Erysipelothrix, and Kurthia 346
23 Bacillus and Recently Derived Genera 357
24 Nocardia, Rhodococcus, Gordona, Actinomadura, Streptomyces, and Other Actinomycetes of Medical Importance 370
25 Mycobacterium 399
26 Algorithms for Identification of Aerobic Gram-Negative Bacteria 438
27 Enterobacteriaceae: Introduction and Identification 442
28 Escherichia, Shigella, and Salmonella 459
29 Klebsiella, Enterobacter, Citrobacter, and Serratia 475
30 Yersinia and Other Enterobacteriaceae 483
31 Vibrio 497
32 Aeromonas and Plesiomonas 507
33 Pseudomonas 517
34 Burkholderia, Stenotrophomonas, Ralstonia, Brevundimonas, Comamonas, and Acidovorax 526
35 Acinetobacter, Alcaligenes, Moraxella, Methylobacterium, and Other Nonfermentative Gram-Negative Rods 539
36 Actinobacillus, Capnocytophaga, Eikenella, Kingella, and Other Fastidious or Rarely Encountered Gram-Negative Rods 561
37 Legionella 572
38 Neisseria and Branhamella 586
39 Haemophilus 604
40 Bordetella 614
41 Brucella 625
42 Pasteurella 632
43 Bartonella and Afipia 638
44 Francisella 647
45 Algorithm for Identification of Anaerobic Bacteria 652
46 Clostridium 654
47 Peptostreptococcus, Propionibacterium, Lactobacillus, Actinomyces, and Other Non-Spore-Forming Anaerobic Gram-Positive Bacteria 672
48 Bacteroides, Porphyromonas, Prevotella, Fusobacterium, and Other Anaerobic Gram-Negative Rods and Cocci 690
49 Algorithms for Identification of Curved and Spiral-Shaped Gram-Negative Rods 712
50 Campylobacter and Arcobacter 716
51 Helicobacter 727
52 Leptospira and Leptonema 739
53 Borrelia 746
54 Treponema and Other Host-Associated Spirochetes 759
55 Algorithms for Identification of Mycoplasmas, Ureaplasma, and Obligate Intracellular Bacteria 777
56 Mycoplasma and Ureaplasma 782
57 Chlamydia 795
58 Rickettsia 807
59 Coxiella 815
60 Ehrlichia 821
Sect. V Virology 832
61 Taxonomy and Classification of Viruses 835
62 Algorithms for Detection and Identification of Viruses 843
63 Human Immunodeficiency Viruses 847
64 Human T-Cell Lymphotropic Virus Types I and II 871
65 Herpes Simplex Viruses 878
66 Human Cytomegalovirus 888
67 Varicella-Zoster Virus 900
68 Epstein-Barr Virus 912
69 Human Herpesviruses 6, 7, and 8 and Herpes B Virus 919
70 Influenza Viruses 928
71 Parainfluenza Viruses 936
72 Respiratory Syncytial Virus 942
73 Measles Virus 951
74 Mumps Virus 959
75 Rubella Virus 964
76 Adenoviruses 970
77 Rhinoviruses 983
78 Enteroviruses 990
79 Rotaviruses 999
80 Caliciviruses, Astroviruses, and Other Diarrheic Viruses 1005
81 Hepatitis A Virus 1014
82 Hepatitis B and D Viruses 1025
83 Hepatitis C and G Viruses 1043
84 Hepatitis E Virus 1053
85 Human Papillomavirus 1070
86 Polyomaviruses 1080
87 Human Parvoviruses 1089
88 Rabies Virus 1099
89 Arboviruses 1107
90 Filoviruses and Arenaviruses 1125
91 Poxviruses Infecting Humans 1137
92 Transmissible Spongiform Encephalopathies 1145
Sect. VI Mycology 1159
93 Taxonomy, Classification, and Morphology of the Fungi 1161
94 Algorithms for Detection and Identification of Fungi 1167
95 Candida, Cryptococcus, and Other Yeasts of Medical Importance 1184
96 Pneumocystis 1200
97 Aspergillus, Fusarium, and Other Opportunistic Moniliaceous Fungi 1212
98 Rhizopus, Rhizomucor, Absidia, and Other Agents of Systemic and Subcutaneous Zygomycoses 1242
99 Histoplasma, Blastomyces, Coccidioides, and Other Dimorphic Fungi Causing Systemic Mycoses 1259
100 Trichophyton, Microsporum, Epidermophyton, and Agents of Superficial Mycoses 1275
101 Bipolaris, Exophiala, Scedosporium, Sporothrix, and Other Dematiaceous Fungi 1295
102 Fungi Causing Eumycotic Mycetoma 1318
Sect. VII Parasitology 1327
103 Taxonomy and Classification of Human Parasites 1329
104 Algorithms for Detection and Identification of Parasites 1336
105 Plasmodium and Babesia 1355
106 Leishmania and Trypanosoma 1365
107 Toxoplasma 1374
108 Pathogenic and Opportunistic Free-Living Amebae 1383
109 Intestinal and Urogenital Amebae, Flagellates, and Ciliates 1391
110 Cryptosporidium, Cyclospora, and Isospora 1406
111 Microsporidia 1413
112 Intestinal Helminths 1421
113 Tissue Helminths 1436
114 Arthopods of Medical Importance 1449
Sect. VIII Antimicrobial Agents and Susceptibility Testing 1467
115 Antimicrobial Susceptibility Testing: General Considerations 1469
116 Antibacterial Agents 1474
117 Mechanisms of Resistance to Antimicrobial Agents 1505
118 Antibacterial Susceptibility Tests: Dilution and Disk Diffusion Methods 1526
119 Susceptibility Testing of Fastidious Bacteria 1544
120 Susceptibility Testing of Anaerobic Bacteria 1555
121 Special Phenotypic Methods for Detecting Antibacterial Resistance 1563
122 Genetic Methods for Detecting Antibacterial and Antiviral Resistance Genes 1578
123 Susceptibility Testing Instrumentation and Computerized Expert Systems for Data Analysis and Interpretation 1593
124 Antimycobacterial Agents and Susceptibility Tests 1601
125 Antiviral Agents and Susceptibility Tests 1624
126 Antifungal Agents and Susceptibility Tests 1640
127 Antiparasitic Agents and Susceptibility Tests 1653
Sect. IX Reagents, Stains, and Media 1663
128 Reagents 1665
129 Stains 1674
130 Media 1687
Author Index 1709
Subject Index 1711
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  • Anonymous

    Posted April 6, 2001

    A laboratory must have...

    An essential tool for all clinical microbiology laboratories. This book should be considered your bible. It contains current data relating to identification, clinical significance, and treatment of every group of clinically relevant organisms. It also contains material relative to processing, testing procedures, and general laboratory practices. If you only have one reference book in your lab, this should be it.

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