Manual of Clinical Psychopharmacology / Edition 7

Manual of Clinical Psychopharmacology / Edition 7

by Jonathan O. Cole, Charles DeBattista
     
 

ISBN-10: 1585623776

ISBN-13: 9781585623778

Pub. Date: 04/21/2010

Publisher: American Psychiatric Publishing, Incorporated

Revised by preeminent psychopharmacologists, the book presents systematic, comprehensive, yet utterly accessible information and practical advice for applying psychotropic medications to the treatment of specific psychiatric conditions.

American Psychiatric Publishing

Overview

Revised by preeminent psychopharmacologists, the book presents systematic, comprehensive, yet utterly accessible information and practical advice for applying psychotropic medications to the treatment of specific psychiatric conditions.

American Psychiatric Publishing

Product Details

ISBN-13:
9781585623778
Publisher:
American Psychiatric Publishing, Incorporated
Publication date:
04/21/2010
Edition description:
Seventh Edition
Pages:
744
Product dimensions:
5.50(w) x 8.20(h) x 1.70(d)
Age Range:
18 Years

Table of Contents


Preface     xxiii
General Principles of Psychopharmacological Treatment     1
General Advice     3
Practice Guidelines     4
Legal, Ethical, and Economic Issues     4
Bibliography     12
Diagnosis and Classification     15
Mood Disorders     17
Bipolar Disorders     17
Depressive Disorders     19
Schizophrenia and Other Schizophrenia Spectrum Disorders     22
Anxiety Disorders     24
Somatoform Disorders     28
Personality Disorders     28
Psychoactive Substance Use Disorders     29
Child and Adolescent Disorders     30
FDA Approval of Symptom Reduction Strategies     31
DSM-V and Pharmacogenetics     31
Summary     32
Bibliography     32
Antidepressants     35
History     38
General Principles of Antidepressant Use     40
Choosing an Antidepressant     40
Dosage and Administration     44
Duration of Treatment     44
Selective Serotonin Reuptake Inhibitors     46
Pharmacological Effects     46
Indications     51
Side Effects     54
Overdose     61
Drug Interactions     61
Dosage and Administration     53
Discontinuation     67
5-HT[subscript 2] Receptor Antagonists (Trazodone and Nefazodone)     69
Pharmacological Effects     70
Indications     71
Side Effects     72
Overdose     75
Drug Interactions     76
Dosage and Administration     77
Discontinuation     78
Selective Serotonin-Norepinephrine Reuptake Inhibitors (Venlafaxine and Duloxetine)     78
Pharmacological Effects     79
Indications     80
Side Effects     82
Overdose     83
Drug Interactions     83
Dosage and Administration     84
Discontinuation     85
Combined Noradrenergic-Dopaminergic Antidepressant (Bupropion)     85
Pharmacological Effects     86
Indications     87
Side Effects     89
Overdose     89
Drug Interactions     90
Dosage and Administration     90
Mirtazapine     90
Pharmacological Effects      90
Indications     92
Side Effects     93
Overdose     95
Drug Interactions     95
Dosage and Administration     95
Norepinephrine Reuptake Inhibitors: Reboxetine and Atomoxetine     96
Pharmacological Effects     96
Indications     97
Side Effects     98
Overdose     99
Dosage and Administration     99
Drug Interactions     99
Discontinuation     99
Gepirone     100
Tricyclic and Tetracyclic Antidepressants     101
Structures     101
Pharmacological Effects     101
Indications     106
Blood Levels     107
Side Effects     112
Overdose     115
Dosage and Administration     115
Discontinuation     117
Monoamine Oxidase Inhibitors     118
Pharmacological Effects     118
Indications     118
Side Effects     121
Overdose     125
Drug Interactions     125
Dosage and Administration     128
Discontinuation     128
Selective and Reversible Monoamine Oxidase Inhibitors     129
Melatonin Agonist-5-HT[subscript 2C] Antagonist     133
Novel Antidepressants     134
Bibliography     136
Antipsychotic Drugs     159
General Principles of Antipsychotic Use     162
The Drugs     162
Efficacy     168
Acute Antipsychotic Treatment     171
Early Inpatient Treatment     175
Maintenance Drug Therapy     178
Use in Other Psychiatric Disorders     182
Atypical Antipsychotics     189
Clozapine     189
Risperidone     200
Olanzapine     203
Quetiapine     207
Ziprasidone     210
Aripiprazole     212
Standard (Typical) Antipsychotics     214
Side Effects     216
Haloperidol Decanoate     231
Other Options for Treating Negative Symptoms     232
Alternatives to Antipsychotic Therapy     234
Antipsychotic Drugs in Development     236
Bibliography     238
Mood Stabilizers     255
Lithium     257
History and Indications     257
Pharmacological Effects      261
Clinical Indications     262
Side Effects     269
Preparations     276
Dosage and Administration     277
Use in Pregnancy     279
Lithium Information Center     280
Anticonvulsants     280
Valproate     281
Carbamazepine     294
Lamotrigine     301
Other Anticonvulsants     306
Antipsychotics     317
Benzodiazepines     319
Calcium Channel Blockers     320
Omega-3 Fatty Acids     321
Bibliography     322
Antianxiety Agents     337
Benzodiazepines     340
Indications     340
Pharmacological Effects     342
Subclasses     343
Dosage and Administration     348
Withdrawal     352
Side Effects     355
Overdose     355
Antidepressants     356
Agoraphobia and Panic     356
Generalized Anxiety Disorder     357
Social Phobia     358
Body Dysmorphic Disorder     360
Posttraumatic Stress Disorder     360
Obsessive-Compulsive Disorder     364
Anticonvulsants     366
Antipsychotics     368
Noradrenergic Agents     369
Clinical Indications     369
Dosage and Administration     370
Side Effects     371
Antihistamines     372
Buspirone     372
Barbiturates     375
Amobarbital Sodium (Amytal) as a Parenteral Solution     377
Catatonia     382
Meprobamate     384
Bibliography     386
Hypnotics     395
Insomnia     395
Behavioral Approaches     401
Pharmacological Approaches     401
Benzodiazepine Hypnotics     403
Nonbenzodiazepine Hypnotics     409
Melatonin Receptor Agonist: Ramelteon     411
Sedative Antihistamines and Other Nonbenzodiazepine Psychoactive Drugs With Hypnotic Properties     412
Barbiturates     414
Nonbarbiturate Hypnotics     417
Methaqualone     419
Over-the-Counter Sleeping Agents     420
L-Tryptophan     420
Melatonin     421
Valerian Extract     422
General Conclusions      423
Bibliography     425
Stimulants and Other Fast-Acting Drugs     429
Amphetamine Abuse     434
Uses of Stimulants     436
Attention-Deficit/Hyperactivity Disorder     436
Depression     439
Acquired Immunodeficiency Syndrome     443
Other Medical Conditions     444
Drug Combinations     444
Psychosis     445
Stimulant Use Versus Abuse     446
Other Fast-Acting Drugs     447
Bibliography     449
Augmentation Strategies for Treatment-Resistant Disorders     453
Augmentation Strategies for Depression     454
Lithium-Antidepressant Combinations     454
Thyroid Supplement-Antidepressant Combinations     457
Estrogen, DHEA, and Testosterone Combinations With Antidepressants     460
Dopamine Agonist-Antidepressant Combinations     463
Monoamine Precursor-Antidepressant Combinations     464
SSRI Combinations     465
Antipsychotic-Antidepressant Combinations     469
Other TCA Combinations     471
Augmentation Strategies for Bipolar Disorder     473
Combinations of Two or More Mood Stabilizers     473
Mood Stabilizer-Antipsychotic Combinations     475
Mood Stabilizer-Antidepressant Combinations     477
Mood Stabilizers and Omega-3 Fatty Acids     478
Augmentation Strategies for Schizophrenia     479
Combinations of Two Antipsychotics     479
Combinations of Antidepressants and Antipsychotics     480
Combinations of Mood Stabilizers and Antipsychotics     481
Other Augmentation Strategies     483
Bibliography     484
Emergency Room Treatment     499
Agitation and Violence     500
Depression and Suicidality     504
Acute Psychotic Reactions     508
Mixed Psychotic Reactions     508
Schizophrenic, Schizophreniform, and Manic Psychoses     509
Delirium     511
Severe Anxiety     512
Stupor and Catatonia     513
Emergency Room Referrals     514
Bibliography     515
Pharmacotherapy for Substance Use Disorders     519
Drug Testing     521
Stimulants     522
Opiates     523
Detoxification     523
Maintenance     526
Sedatives and Hypnotics     530
Detoxification      530
Pentobarbital Tolerance Test     531
Benzodiazepines     532
Alcohol     534
Maintenance Treatment     537
Cannabis     541
Hallucinogens     542
Phencyclidine     542
Bibliography     543
Pharmacotherapy in Special Situations     549
Pregnancy     549
Pediatric Psychopharmacology     556
Stimulants     557
Antipsychotics     561
Antidepressants     565
Mood Stabilizers     568
Antianxiety Drugs     570
Geriatric Psychopharmacology     571
Antidepressants     572
Hypnotics and Anxiolytics     574
Mood Stabilizers     575
Antipsychotics     576
Medications for Dementia     578
Medications for Agitation     582
Mental Retardation     584
Medical Conditions     587
Psychiatric Disorders Resulting From Medical Illness     587
Psychiatric Disorders Associated With Nonpsychiatric Drugs     590
Psychiatric Disorders Complicated by Medical Disorders     591
Conclusion      601
Bibliography     601
Herbals and Dietary Supplements     619
St. John's Wort (Hypericum Perforatum)     621
Uses     623
Mechanism of Action     624
Side Effects and Drug Interactions     624
Dosage and Administration     625
Omega-3 Fatty Acids     625
Uses and Mechanism of Action     626
Side Effects and Drug Interactions     626
Dosage and Administration     627
Kava (Piper Methysticum)     627
Uses     627
Mechanism of Action     627
Side Effects and Drug Interactions     628
Dosage and Administration     628
Valerian (Valeriana Officinalis)     629
Uses     629
Mechanism of Action     629
Side Effects and Drug Interactions     629
Dosage and Administration     630
Ginkgo (Ginkgo Biloba)     630
Uses     630
Mechanism of Action     630
Side Effects and Drug Interactions     630
Dosage and Administration     631
Folate and B Vitamins     631
S-Adenosylmethionine (SAMe)     632
Uses      632
Mechanism of Action     633
Side Effects and Drug Interactions     633
Dosage and Administration     633
Inositol     634
Uses     634
Mechanism of Action     634
Side Effects and Drug Interactions     635
Dosage and Administration     635
DHEA (Dehydroepiandrosterone)     635
Uses     635
Mechanism of Action     636
Side Effects and Drug Interactions     636
Dosage and Administration     636
Bibliography     636
Strengths and Costs of Antidepressant and Antipsychotic Drugs     641
Suggested Readings     645
Index     647

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