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Doody's Review ServiceReviewer: John F. Moran, MD (Loyola University Stritch School of Medicine)
Description: This detailed book on hypertension, edited by seven physicians and written by 74 international contributors, has nine sections covering blood pressure measurement to drug treatments and therapeutic strategies.
Purpose: The purpose is to provide background material on hypertension and its pathophysiology, but with a focus on practical diagnostic and treatment aspects. The book goes far beyond background material.
Audience: All physicians treating patients with hypertension will find much information here.
Features: A book focused on hypertension is very important since about 20 percent of the population is hypertensive and in only 20 percent of those is it adequately controlled. The book begins with a study of epidemiology and the antihypertensive trials. The pathophysiology of hypertension is detailed with much information on the renal angiotensin aldosterone system, neurocentral hypertension, and even rare causes of hypertension such as Bartter's Syndrome, pheochromocytoma, as well as renal artery stenosis and corticoadrenal hypertension. Section 6 on drug treatment reviews data from trials on all drugs: beta blockers, calcium channel blockers, ACE inhibitors, as well as Alpha I blockers and angiotensin receptor blockers, and others such as Minoxidil and Clonidine. There are many tables of drugs with dosages, there are also details on newer antyhypertensive medications now in drug trials. Given that hypertension should be treated, the authors detail the goals of blood pressure lowering and consider the JNC VI Guidelines which suggest pressures below 140/90 and in some instances, blood pressures in the 130s/80s would be better. There are sections on the management of hypertension in different patient groups: adolescents, elderly patients, diabetics, pregnant patients, transplant patients, as well as patients with many coronary risk factors. The book is well referenced and has many tables. Each chapter also has pink colored boxes which focus on side bar issues such as meta analysis, reninism, the physiology of the plasma membrane and the conditions needed for proper blood pressure measurements.
Assessment: This comprehensive detailed analysis of hypertension also includes animal studies, experimental forms of hypertension, and genetic analysis. All aspects of the management of hypertension are well covered. In addition, the book is reader friendly with color coded sections as well as subtitles in the upper outer corner of every page. This is a welcome addition to the literature of hypertension.