Manual of Hypertension / Edition 1

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The aim is to produce a really practical manual that gives clearly presented guidelines to the ordinary practitioner about what to do in given circumstances. It will be a "bench book" on hypertension, in which its various aspects are dealt with from a clinical perspective, and where the text is constructed, laid out, and illustrated, in such a way as to make the work of maximum utility and readability to the practitioner.

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Editorial Reviews

Doody's Review Service
Reviewer: John F. Moran, MD (Loyola University Stritch School of Medicine)
Description: This detailed book on hypertension, edited by seven physicians and written by 74 international contributors, has nine sections covering blood pressure measurement to drug treatments and therapeutic strategies.
Purpose: The purpose is to provide background material on hypertension and its pathophysiology, but with a focus on practical diagnostic and treatment aspects. The book goes far beyond background material.
Audience: All physicians treating patients with hypertension will find much information here.
Features: A book focused on hypertension is very important since about 20 percent of the population is hypertensive and in only 20 percent of those is it adequately controlled. The book begins with a study of epidemiology and the antihypertensive trials. The pathophysiology of hypertension is detailed with much information on the renal angiotensin aldosterone system, neurocentral hypertension, and even rare causes of hypertension such as Bartter's Syndrome, pheochromocytoma, as well as renal artery stenosis and corticoadrenal hypertension. Section 6 on drug treatment reviews data from trials on all drugs: beta blockers, calcium channel blockers, ACE inhibitors, as well as Alpha I blockers and angiotensin receptor blockers, and others such as Minoxidil and Clonidine. There are many tables of drugs with dosages, there are also details on newer antyhypertensive medications now in drug trials. Given that hypertension should be treated, the authors detail the goals of blood pressure lowering and consider the JNC VI Guidelines which suggest pressures below 140/90 and in some instances, blood pressures in the 130s/80s would be better. There are sections on the management of hypertension in different patient groups: adolescents, elderly patients, diabetics, pregnant patients, transplant patients, as well as patients with many coronary risk factors. The book is well referenced and has many tables. Each chapter also has pink colored boxes which focus on side bar issues such as meta analysis, reninism, the physiology of the plasma membrane and the conditions needed for proper blood pressure measurements.
Assessment: This comprehensive detailed analysis of hypertension also includes animal studies, experimental forms of hypertension, and genetic analysis. All aspects of the management of hypertension are well covered. In addition, the book is reader friendly with color coded sections as well as subtitles in the upper outer corner of every page. This is a welcome addition to the literature of hypertension.
From The Critics
This manual provides practical advice on a range of problems related to the diagnosis and management of both primary and secondary hypertension. The nine chapters, written and edited by physicians and researchers, discuss how elevated blood pressure might originate, why it represents a risk factor, and how the condition can be diagnosed and managed. Topics include epidemiology, etiology and pathophysiology, blood pressure measurement, specific secondary causes of hypertension, essential hypertension, antihypertensive drugs, treatment strategies, special conditions, and changing aspects of hypertension. Although intended for cardiologists, the information is presented in an accessible manner that would be of use and interest to the patient. Annotation c. Book News, Inc., Portland, OR (

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780443061950
  • Publisher: Elsevier Health Sciences
  • Publication date: 11/30/2001
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 736
  • Product dimensions: 7.40 (w) x 9.70 (h) x 1.40 (d)

Table of Contents

Introduction: How to use this book The Editor

Section 1. Epidemiology Julius

1.1 Hypertension as a cardiovascular risk factor Dr W Kannel
1.2 Results of intervention trials Professor R Fagard

Section 2. Etiology and Pathophysiology Julius

2.1 The animal modes of hypertension Professor A Ferrari
2.2 Hypertension as a genetic disease Professor P Hamet
2.3 Salt and other dietary factors Dr I Puddey
2.4 The renin-angiotension system Professor M Nicholls
2.5 Neural factors Professor M Esler
2.6 Hormones and other humoral factors Dr O Carretero
2.7 Cell membrane abnormalities Dr A Semplicini

Section 3. Blood pressure measurement Mancia

3.1 Office assessment of blood pressure Dr M Weber
3.2 Home blood pressure Professor J Mallion
3.3 Ambulatory blood pressure Dr G Parati
3.4 Special blood pressure measuring devices Professor E OBrien
Section 4. Specific (secondary) causes of hypertension Saruta

4.1 Renovascular hypertension Professor J Pohl
4.2 Renal parenchymal hypertension Professor M Epstein
4.3 Phaeocromocytoma Dr G Grassi
4.4 Cortico-adrenal hypertension Professor J Whitworth
4.5 Rare forms of secondary hypertension Professor R Gordon
4.6 Hypertension from exogenous substances Dr Y Saruta

Section 5. Essential hypertension Weber

5.1 Diagnosing essential hypertension
5.2 Excluding secondary causes of hypertension Dr A Morganti
5.3 Routine assessment of end-organ damage Dr L Hansson
5.4 Special measurer of end-organ damage Dr T Pickering

Section 6. Antihypertensive drugs Chalmers
6.1 Diuretics
6.2 Beta-blockers Dr B Prichard
6.3 Calcium antagonists Professor F Meredith
6.4 ACE inhibitors Professor D Clement
6.5 Alpha-blockers Dr H Elliot
6.6 Angiotensin II receptor antagonists Dr J Reid
6.7 Central agents Professor P van Zweiten
6.8 Other drugs Professor A Pessina

Section 7. Treatment strategies selecting the proper Weber therapeutic agent

7.1 Goal blood pressure Professor A Zanchetti
7.2 Life-style changes Dr L Beilin
7.3 The step-care approach Dr B Materson
7.4 The substitution and other approaches Professor P de Leeuw
7.5 The pros and cons of fixed combinations
7.6 The problem of compliance to treatment Dr B Waeber

Section 8. Treatment in special conditions Ferrari

8.1 Hypertension in children and adolescents Dr B Falkner
8.2 Hypertension in the elderly Professor F Messerli
8.3 Hypertension in blacks Dr K Jamerson
8.4 The patients with multiple risk factors Dr G Jennings
8.5 The diabetic hypertension patient
8.6 Hypertension in pregnancy Dr M Brown
8.7 Hypertension in transplant patients Dr A Mimran
8.8 Resistant hypertension Dr K Rahn

Section 9 Changing aspects of hypertension Chalmers

9.1 Malignant hypertension Dr Y Seedat
9.2 Impact of guidelines in the clinical practice Professor J Chalmers
9.3 Failure of antihypertensive treatment in the population Dr S Oparil
Assessment of cost-benefit of antihypertensive Prof E Ambrosioni treatment
9.5 Isolated office hypertension Professor G Mancia

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