Master Control Genes in Development and Evolution: The Homeobox Story

Master Control Genes in Development and Evolution: The Homeobox Story

by Walter J. Gehring
     
 

ISBN-10: 0300074093

ISBN-13: 9780300074093

Pub. Date: 11/28/1998

Publisher: Yale University Press

In this book, one of the world's most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he…  See more details below

Overview

In this book, one of the world's most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he explains how this has provided the key to our modern understanding of development and evolution. The book thus becomes not only a lucid discussion of genetics but also an engaging description of the art of scientific investigation.

Product Details

ISBN-13:
9780300074093
Publisher:
Yale University Press
Publication date:
11/28/1998
Series:
Terry Lectures Series
Edition description:
New Edition
Pages:
254
Product dimensions:
6.48(w) x 9.53(h) x 1.00(d)

Table of Contents

Foreword
Preface
Chronology
1The Ancient Language of Genes1
2The Key to Understanding Development: Homeotic Genes21
3Gene Cloning and the Discovery of the Homeobox39
4How to Generate an Embryo?55
5The Secret is in the Egg93
6From Gradients to Stripes107
7The Master Control Genes123
8The Molecular Basis137
9Enhancer Trapping and Hunting for Target Genes153
10The Wiring of the Nervous System163
11Metamorphosis and Transdetermination171
12The Role of Homeotic Genes in Evolution181
13A Deep Look into the Eyes197
App. 1Theories About Fertilization211
App. 2Sperm and Inheritance212
App. 3Drosophilia Life Cycle213
Glossary215
Further Reading221
Index227

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