Description:This pocket reference for busy healthcare professionals is divided into four sections covering fundamentals of antimicrobial agents, antimicrobial dosing in adults and children, treatment of specific organisms, and infectious syndromes in adults.
Purpose:It is intended as a simplified, quick guide for the broad area of infectious diseases and antimicrobial therapy. Certainly, the area of infectious diseases and antimicrobial therapy is vast and, although there are online references and books devoted to this area, this pocket reference provides a readily accessible guide. This book serves as a good pocket guide for this busy clinician.
Audience:The audience includes practitioners (medical and pharmacy), residents (medical and pharmacy), and all healthcare students who would like to have a readily available resource. The authors are infectious disease authorities who practice at Mayo Clinic.
Features:The guide starts out with some of the basics of antimicrobials, including spectrum of activity, pharmacokinetics, and major side effects, mostly in table format. This is followed by tables for appropriate dosing based on creatinine clearances. It discusses dosing during CRRT, which is unique. The guide details appropriate vancomycin and aminoglycoside dosing based on current guidelines at Mayo Clinic and pediatric dosing of antimicrobials. The next section on preferred and alternative antimicrobials for specific bacteria, fungi, and viruses uses tables that include the preferred and alternative drug(s), but without recommended dosing. The last section is largely devoted to infectious syndromes in adults and the common diagnostic and treatment modalities for these syndromes. Here, some of the syndromes include first-line and alternative antimicrobial agents including dosing and some have the first-line and alternative agents. The enhanced readability of the tables is an asset, but the lack of references is a shortcoming.
Assessment:This pocket guide covers many of the same areas, but not in as much detail as the standard in this field, The Sanford Guide to Antimicrobial Therapy 2009, 39th edition, Gilbert et al. (Antimicrobial Therapy, Incorporated, 2009). The advantages of the Sanford Guide are the references and completeness. The advantages of this guide are its readability and CVVH tables.