Disc 1
- Falling Rain Blues - John Arnold - Lonnie Johnson
- Jinx Blues - Ora Brown - Tiny Parham
- Dark Night Blues - Blind Willie McTell
- Pony Blues - Charley Patton
- Milk Cow Blues - Kokomo Arnold
- Labor Blues - Tom Dickson
- Shake 'Em on Down - Bukka White
- Lonesome Home Blues - Tommy Johnson
- No Place to Go - Walter Davis
- Cotton Seed Blues - Roosevelt Sykes
- Dry Spell Blues, Pt. 1 - Son House
- Steamboat Man Blues - John Anderson - Porter Grainger - Freddie Jenkins - Clara Smith
- Gravel Camp Blues - Lewis Black
- Blue Monday Blues - Lovie Austin - Ida Cox
- Rock and Gravel Blues - Peg Leg Howell
- The Right String But the Wrong Yo-Yo - Speckled Red
- Make Than Gravel Fly - Paul George - Slick Helms - Hattie Snow - Syd Valentine - Valentine
- Rock Island Blues - Lewis Black
- Crazy Blues - Dope Andrews - Perry Bradford - Johnny Dunn - Ernest Elliott - Jazz Hounds - Leroy Parker - Mamie Smith
- Snatch It Back Blues - Buddy Boy Hawkins
- John Henry - Henry Thomas
- Cannonball Blues - Furry Lewis
- Friendless City Blues - Walter Roland - Joshua White
- Stocking Feet Blues - Blind Lemon Jefferson
- Stranger's Blues - Sippie Wallace - Clarence Williams
- Wintertime Blues - Bill Gaither - Bill "J. Leroy's Buddy" Gaither - Honey Hill
Disc 2
- New Way of Living Blues - Ramblin' Thomas
- Black Gal Makes Thunder - Rudy Foster
- Three Women Blues - Blind Willie McTell
- Yellow Girl Blues - Texas Alexander - Lonnie Johnson
- Gonna Ramble Blues - Sara Martin - Sylvester Weaver
- Brown Skin Man - Lovie Austin - Austin - Edmonia Henderson - Tommy Ladnier - Jimmy O'Bryant
- Brown Skin Gal - Barbecue Bob
- Brown Skin Blues - Lillian Glinn - Willie Tyson
- Chocolate to the Bone - Barbecue Bob
- Kitchen Mechanic Blues - James C. Brown - Johnny Brown - Excelsior Quartette - Vernon Jones - C.C. Parker
- Black Evil Blues - Henry Brown - Alice Moore - Ike Rodgers
- Outside Woman Blues - Blind Joe Reynolds
- Reckless Woman - Lucille Bogan - Walter Roland
- It Won't Be Long - Charley Patton
- Little and Low - Roosevelt Sykes
- Big Fat Mama Blues - Tommy Johnson
- My Pencil Won't Write No More - Bo Carter
- Signifying Blues - Sam Collins
- Black Snake Moan - Blind Lemon Jefferson
- Save My Jelly - Cow Cow Davenport - Iva Smith
- Freakish Man Blues - George Hannah - Meade "Lux" Lewis
- Sissy Man Blues - Kokomo Arnold
- Prove It on Me Blues - Georgia Tom - Martell Pettiford - Ma Rainey - Rainey - Carl Reid
- B.D. Woman's Blues - Lucille Bogan
- The Dirty Dozen - Speckled Red
- Jacksonville Blues - Barbecue Bob - Nellie Florence - Charley Lincoln
Disc 3
- Mojo Hand Blues - Lovie Austin - Shirley Clay - Ida Cox - Johnny Dodds - Lovie Austin & Her Blues Serenaders - Kid Ory - Albert Wynn
- Mojo Hidin' Woman - Blind Boy Fuller
- Papa's Got Your Water On - Charlie Burse - Hattie Hart - Hambone Lewis - Memphis Jug Band - Ben Ramey - Will Shade
- "Toby" Woman Blues - Gene Campbell
- Squinch Owl Moan - Jed Davenport - Too Tight Henry
- Black Cat Blues - John Chapman - Old Pal Smoke Shop Four
- Broke and Hungry - Blind Lemon Jefferson
- Wish I Had You (And I'm Gonna Get You Blues) - Porter Grainger - Viola McCoy
- Bad Boy - Ed Bell
- Doggone My Good Luck Soul - Hattie Hudson - Willie Tyson
- Black Cat Moan - Gus Aiken - Clara Smith and Her Five Black Kittens - Bob Fuller - Stanley Miller - Clara Smith
- Those Black Man Blues - Henry Brown - Mary Johnson - Ike Rodgers
- Seven Sisters Blues, Pt. 1 - Funny Paper Smith
- Seven Sisters Blues, Pt. 2 - Funny Paper Smith
- Aunt Caroline Dyer Blues - Charlie Burse - Hambone Lewis - Memphis Jug Band - Ben Ramey - Will Shade
- I'm a Gamblin' Woman - Memphis Minnie
- Skin Game Blues - Peg Leg Howell
- Gamblin' Charley - Charley Lincoln
- If You Lose Your Good Gal, Don't Mess with Mine - George Noble
- Jack O' Diamond Blues [Take 2] - Blind Lemon Jefferson
- Stack O' Lee Blues - Mississippi John Hurt
- Policy Dream Blues - Bumble Bee Slim - Myrtle Jenkins
- Policy Wheel Blues - Kokomo Arnold
- Four Eleven Forty Four - Papa Charlie Jackson
- Three Sixty Nine Blues - Charlie "Little Buddy" Doyle - Big Walter Horton - Jack Kelly - Willie "Willie Tango" Shaw
- The Clearing House Blues - Charlie Dixon - Clara Smith
Disc 4
- Mississippi Jail House Groan - Rube Lacey
- Lonesome Blues - Eddie Anthony - Henry Williams
- Old Rounder's Blues - Blind Lemon Jefferson
- Moon Going Down - Willie Brown - Charley Patton
- Smack That Thing - Walter Coleman
- I Had to Smack That Thing - Frances "Barrelhouse Frankie" Wallace
- I Had to Come Back Home Blues - Katherine Baker - James Johnson - Lonnie Johnson
- Rowdy Blues - Kid Bailey - Willie Brown - Charley Patton
- Barrelhouse When It Rains - Black Bob - Big Bill Broonzy - Bill Settles
- Blues in the Alley - Hot Box Johnson - Curtis Jones - Fred Williams
- Old Jim Canaan's - Kid Spoons - Ernest "Son Joe" Lawlers - Robert Wilkins
- On the Wall - Willie Brown - Louise Johnson - Charley Patton
- Beaver Slide Rag - Eddie Anthony - Peg Leg Howell - Henry Williams
- Low Down Mississippi Bottom Man - Freddie Spruell
- You Got to Reap What You Sow - Tampa Red
- Sitting on Top of the World - Lonnie Chatman - Mississippi Sheiks - Walter Vinson
- Some Summer Day, Pt. 1 - Charley Patton
- I'm Still Sitting on Top of the World - Sam Collins
- Mama Blues - William McCoy
- Friday Moan Blues - Alfred Lewis
- Violin Blues - Nap Hayes - Lonnie Johnson - Matthew Prater
- Shaking Weed Blues - Tommy Settles
- Fairasee Woman (Memphis Woman) - Kokomo Arnold - Peetie Wheatstraw
- Spike Driver Blues - Mississippi John Hurt
- Waking Blues - Otis Harris