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Linda J. RichardsThis book represents a step toward a closer dialogue between theoreticians and experimentalists, a step that can only further our understanding of the brain.
In contrast to other texts of developmental biology, Mechanisms of Cor tical Development integrates information on regulatory processes at th e levels of molecules, cells and metworks. The authors draw together a n extensive literature on cellular development and structural morpholo gy, biochemical and genetic events and hypotheses that have been subje ct to mathematical modelling. Important metholdogies, such as transgen ics and formal modelling, are explained for the non-specialist. Major future challenges are clearly identified. This is a unique contributio n to the literature, combining the fundamentals of experimental develo pmental neurobiology with accessible neural modelling. It will be esse ntial reading for neuroscientists in general as well as those with a p articular interest in development.
The book contains black-and-white illustrations.
Chapter 1 - Introduction
Chapter 2 - Early development of the telencephalon
Chapter 3 - Molecular recognition of early forebrain and cortical development
Chapter 4 - Guidance of axons and innervation of cortical structures
Chapter 5 - Map formation
Chapter 6 - Mechanisms controlling the development of cortical connections at the target
Chapter 7 - Functional development of the cortex