Mechanisms of Insulin Action / Edition 1

Mechanisms of Insulin Action / Edition 1

by Alan R. Saltiel, Jeffrey E. Pessin
     
 

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ISBN-10: 1441924698

ISBN-13: 9781441924698

Pub. Date: 03/07/2011

Publisher: Springer New York

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states.

Overview

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Product Details

ISBN-13:
9781441924698
Publisher:
Springer New York
Publication date:
03/07/2011
Series:
Medical Intelligence Unit Series
Edition description:
Softcover reprint of hardcover 1st ed. 2007
Pages:
214
Product dimensions:
6.00(w) x 9.00(h) x 0.48(d)

Table of Contents

Insulin and IGF-I Receptor Structure and Binding Mechanism.- Subcellular Compartmentalization of Insulin Signaling Processes and GLUT4 Trafficking Events.- Regulation of Insulin Action and Insulin Secretion by SNARE-Mediated Vesicle Exocytosis.- Control of Protein Synthesis by Insulin.- Hepatic Regulation of Fuel Metabolism.- Insulin Action Gene Regulation.- Insulin Action in the Islet—-Cell.- Central Regulation of Insulin Sensitivity.- Transgenic Models of Impaired Insulin Signaling.- Insulin Resistance.

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