Mechanisms of Lymphocyte Activation and Immune Regulation VI: Cell Cycle and Programmed Cell Death in the Immune System / Edition 1

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Editorial Reviews

From the Publisher
'This book is a valuable addition to the literature.'
Quarterly Review of Biology, March 1998
Papers from the February 1996 conference survey recent research in programed cell death/apoptosis. Part I deals with the signaling pathways in apoptosis and reviews mechanisms for recognition of apoptotic lymphocytes by macrophages. Part II examines the role of various genes that regulate apoptosis, including the role of Pas, FasL, and other TNF family members. Part III reviews various aspects of apoptosis in B lymphocytes, and Part IV details the analysis of apoptosis in T cells, including the mechanisms of apoptosis in thymocytes and the genes that regulate it. Of interest to basic immunologists and molecular biologists. Annotation c. by Book News, Inc., Portland, Or.
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Product Details

Table of Contents

Apoptosis/Programmed Cell Death: A Brief Historical Perspective; S. Gupta Cell Cycle and Signaling Pathways in Apoptosis: Apoptosis and Its Regulation; J.J. Cohen Mechanisms for Recognition and Phagocytosis of Apoptotic Lymphocytes by Macrophages; R.A. Schlegel, et al. Cytotoxic Lymphocyte Killing Enters the ICE Age S.J. Martin, et al. Crosstalk between Ceramide and PKC Activity in the Control of Apoptosis in WEHI231; S.J. Chmura, et al. Apoptosisregulating Genes: Regulation of Lymphoid Apoptosis by Bc12 and Bc1xL; G. Nuñez, et al. The Epstein-Barr Virus Gene BHRF1, a Homologue of the Cellular Oncogene bcl2, Inhibits Apoptosisinduced by Gamma Radiation and Chemotherapeutic Drugs; N.J. McCarthy, et al. Structure-Function Analysis of Bcl2 Family Proteins: Regulators of Programmed Cell Death; J.C. Reed, et al. Role of ICE-proteases in Apoptosis; V.M. Dixit Fas-mediated Apoptosis; S. Nagata Apoptosis in B Cells: Signals for Survival and Apoptosis in Normal and Neoplastic B Lymphocytes; J. Gordon, et al. Regulation of B Cell Apoptosis R.F. Ashman, et al. Apoptotic Cell Death in the Chicken Bursa of Fabricius; K.A. Jacobsen, et al. Apoptosis in T Cells: The Thymus and T Cell Death; J. Sprent, et al. Genetic Regulation of Apoptosis in the Mouse Thymus; B.A. Osborne, et al. Regulation of T Cell Activation by CD28 and CTLA4; P.J. Noel, et al. 8 additional articles. Index.

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