Mechanisms of Protein Folding / Edition 1

Mechanisms of Protein Folding / Edition 1

by Roger H. Pain
     
 

ISBN-10: 0199637881

ISBN-13: 9780199637881

Pub. Date: 12/28/2000

Publisher: Oxford University Press, USA


The process by which newly synthesized polypeptide chains become their final 3-dimensional protein forms is clearly explained, providing students and researchers of various backgrounds with both a conceptual and technical understanding of the subject. The new Second Edition incorporates the significant improvements in the field such as advances in…  See more details below

Overview


The process by which newly synthesized polypeptide chains become their final 3-dimensional protein forms is clearly explained, providing students and researchers of various backgrounds with both a conceptual and technical understanding of the subject. The new Second Edition incorporates the significant improvements in the field such as advances in interpreting observed kinetic data, the development of technology to observe fast folding reactions, the molten globule state, and the vital role of chaperone proteins in protein folding. The emphasis on experimental approaches has been maintained but this edition does so within the explicit context of simulations and energy surfaces. New discoveries of the central importance of protein folding and unfolding reactions in biology and medicine (including mutation and 'misfolding') are carefully explored. Three case studies elucidate the difficulties of studying protein folding in vivo.

Product Details

ISBN-13:
9780199637881
Publisher:
Oxford University Press, USA
Publication date:
12/28/2000
Series:
Frontiers in Molecular Biology Series, #32
Edition description:
REV
Pages:
480
Product dimensions:
9.30(w) x 7.10(h) x 1.20(d)

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