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Overview

A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an ...
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Overview

A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.
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Product Details

  • ISBN-13: 9781475714241
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 10/31/2013
  • Edition description: Softcover reprint of the original 1st ed. 1979
  • Pages: 430
  • Product dimensions: 6.00 (w) x 9.00 (h) x 0.94 (d)

Table of Contents

Table of Contents
Dopamine and Glutamate in Psychiatric Disorders

Edited by Werner J. Schmidt and Maarten E. A. Reith

Part I. Dopamine

1 Dopamine Receptor Alternative Splicing
Neil M. Richtand, Laurel Pritchard, and Lique M. Coolen

2 Dopamine receptors
Kim A. Neve

Part II: Glutamate

3 Glutamatergic Pathways: Their relevance for psychiatric diseases
Yoland Smith

4 Glutamate receptors: Ionotropic
Daniel T. Monaghan, Julia C.A. More, Bihua Feng, and David Jane

5 Metabotropic Glutamate Receptors
Krystyna Ossowska

Part III: Schizophrenia

6 Dopamine and Schizophrenia
Bart A. Ellenbroek

7 Glutamate and Schizophrenia and the N-methyl-D-aspartate receptor hypofunction hypothesis
Stefan Bleich and Johannes Kornhuber

8 Role of glycine in schizophrenia
Beate D. Kretschmer

Part IV: Depression

9 Dopamine and Depression
Phil Skolnick

10 Glutamate and Depression
Joaquin Del Rio and Diana Frechilla

Part V: Stress and aggression

11 Dopamine, Glutamate and Aggression
Klaus A. Miczek and Eric W. Fish

Part VI: Anxiety

12 Glutamatergic Systems and Anxiety
David N. Stephens

Part VII: Attention Deficit Hyperactivity Disorder

13 Dopamine and Glutamate in ADHD
James M. Swanson, Nora D. Volkow, Jeffrey Newcorn, Betty J. Casey, Robert Moyzis, David K. Grandy, and Michael I. Posner

Part VIII: Addiction

14 Dopamine-Glutamate Interactions in Reward-Related Incentive Learning
Richard J.Beninger and Todor Gerdjikov

15 Sensitization and Relapse: Dopamine-Glutamate Interactions
David A. Baker and Peter W. Kalivas

16 Glutamatergic neurotransmission in sensitization
Thomas M. Tzschentke

17 Glutamatergic mechanisms of drug relapse: Withdrawal and conditioning factors
Anton Y. Bespalov and Robert L. Balster

Part IX: Neurodegeneration

18 Dopamine and neurodegeration
Peter Riederer and Gabriele Gille

19 Glutamate and neurodegeneration
Antonello Novelli, Marcos Perez-Basterrechea, and Maria Teresa Fernández-Sánchez

Part X: Parkinson's Disease

20 Presymptomatic and symptomatic stages of intracerebral inclusion body pathology in idiopathic parkinsońs disease
Heiko Braak and Kelly Del Tredici

21 Dopamine and Glutamate in Parkinson's Disease: Biochemistry, Clinic and Treatment
Heinz Reichmann, Bernd Janetzky, and Peter Riederer

22 Dopamine and glutamate in motor and cognitive symptoms of Parkinson's disease
Werner J. Schmidt

Part XI: Huntington's disease

23 Dopamine and Glutamate in Huntington's disease
Michael S. Levine, Carlos Cepeda, and Marjorie Ariano

Part XII: Dementias

24 Dopaminergic and Glutamatergic Systems in Alzheimer's disease
Paul T. Francis

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