MEDICINAL CHEMISTRY 2E APL

Overview

This book is aimed primarily at final year organic/medicinal chemists considering a research career in drug development.

This Second Edition covers exciting progress recently made with individual drugs and includes a special chapter on the impact of molecular biology on drug design. Other additions to the Second Edition include structure-activity relationships, the role of molecular biology in drug discovery, and drug access and prodrugs. Written for students ...

See more details below
Available through our Marketplace sellers.
Other sellers (Hardcover)
  • All (8) from $38.19   
  • New (1) from $175.00   
  • Used (7) from $38.19   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$175.00
Seller since 2014

Feedback rating:

(187)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
Brand new.

Ships from: acton, MA

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
Page 1 of 1
Showing All
Close
Sort by
Sending request ...

Overview

This book is aimed primarily at final year organic/medicinal chemists considering a research career in drug development.

This Second Edition covers exciting progress recently made with individual drugs and includes a special chapter on the impact of molecular biology on drug design. Other additions to the Second Edition include structure-activity relationships, the role of molecular biology in drug discovery, and drug access and prodrugs. Written for students considering a research career in drug development, this volume is conveniently divided into two parts. The first half introduces readers to the mechanisms of action of drugs and the approaches adopted in designing new drugs. The second half contains chapters written by the discoverers or developers of individual successful drugs who trace the history of the drugs to the present day.

Read More Show Less

Product Details

  • ISBN-13: 9780122741203
  • Publisher: Elsevier Science & Technology Books
  • Publication date: 1/1/1993
  • Edition description: 2ND
  • Edition number: 2
  • Pages: 324
  • Product dimensions: 8.56 (w) x 9.90 (h) x 0.82 (d)

Table of Contents

Contributors
Preface
Glossary
1 Introduction to Receptors and the Action of Drugs 1
2 Structure and Catalytic Properties of Enzymes 19
3 Receptor Pharmacology 37
4 Drug Access and Prodrugs 61
5 QSAR and the Role of Computers in Drug Design 83
6 The Current Status and Future Impact of Molecular Biology in Drug Discovery 103
7 General Approaches to Discovering New Drugs: An Historical Perspective 121
8 Discovery and Development of Cromakalim and Related Potassium Channel Activators 141
9 Angiotensin-Converting Enzyme (ACE) Inhibitors and the Design of Cilazapril 163
10 Beta Blockers 187
11 Salbutamol: A Selective [actual symbol not reproducible]-Stimulant Bronchodilator 209
12 Discovery of Cimetidine, Ranitidine and Other H[subscript 2]-Receptor Histamine Antagonists 228
13 Fluconazole, An Orally Active Antifungal Agent 257
14 Clavulanic Acid and Related Compounds: Inhibitors of [beta]-Lactamase Enzymes 273
Index 295
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)