Medicines from Animal Cell Culture / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$301.53
Used and New from Other Sellers
Used and New from Other Sellers
from $288.79
Usually ships in 1-2 business days
(Save 19%)
Other sellers (Hardcover)
  • All (6) from $288.79   
  • New (6) from $288.79   

Overview

Medicines from Animal Cell Culture focuses on the use of animal cell culture, which has been used to produce human and veterinary vaccines, interferon, monoclonal antibodies and genetically engineered products such as tPA and erythropoietin. It also addresses the recent dramatic expansion in cell-based therapies, including the use of live cells for tissue regeneration and the culture of stem cells.

Medicines from Animal Cell Culture:

  • Provides comprehensive descriptions of methods for cell culture and nutrition as well as the technologies for the preservation and characterisation of both the cells and the derived products
  • Describes the preparation of stem cells and others for use in cell-based therapies – an area of burgeoning research
  • Includes experimental examples to indicate expected results
  • Covers regulatory issues from the UK, the EU and the USA and reviews how these are developing around the world
  • Addresses the key issues of standardisation and validation with chapters on GLP and GMP for cell culture processes

Delivering insight into the exciting world of biological medicines and directions for further investigation into specific topics, Medicines from Animal Cell Culture is an essential resource for researchers and technicians at all levels using cell culture within the pharmaceutical, biotechnology and biomedical industries. It is of value to laboratory managers in these industries and to all those interested in this topic alike.

Read More Show Less

Product Details

  • ISBN-13: 9780470850947
  • Publisher: Wiley
  • Publication date: 7/23/2007
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 696
  • Product dimensions: 6.97 (w) x 9.88 (h) x 1.67 (d)

Meet the Author

Glyn Stacey works at the UK National Institute for Biological Standards and Control and is the Director of the National Stem Cell Bank. 

John Davis edited a successul book on basic cell culture.

Read More Show Less

Table of Contents

Contributors.

Preface.

List of Abbreviations.

1 The Development of Animal Cell Products: History and Overview (B Griffiths).

FUNDAMENTAL ELEMENTS OF CELL GROWTH MEDIA.

2 Water Purity and Regulations (P Whitehead).

3 Development and Optimization of Serum-free and Protein-free Media (D Jayme).

4 Understanding Animal Sera: Considerations for Use in the Production of Biological Therapeutics (R Festen).

CELL ENGINEERING FOR RECOMBINANT PRODUCTS.

5 Expression of Recombinant Biomedical Products from Continuous Mammalian Cell Lines (SA Jeffs).

6 Production of Recombinant Viral Vaccine Antigens (SA Jeffs).

7 A Brief Overview of the Baculovirus Expression System in Insect and Mammalian Cells (C Mannix).

8 Stability: Establishing Clones, Genetic Monitoring and Biological Performance (L Barnes).

9 Gene Transfer Vectors for Clinical Applications (A Meager).

TECHNOLOGY AND FACILITIES FOR CELL CULTURE SCALE-UP.

10 Systems for Cell Culture Scale-up (J Davis).

11 Process Development and Design (DK Robinson and L Chu).

12 Facility Design for Cell Culture Biopharmaceuticals (S Vranch).

13 Monitoring, Control and Automation in Upstream Processing (TS Stoll and P Grabarek).

14 Services and Associated Equipment for Upstream Processing (TS Stoll).

15 System and Process Validation (N Chesterton).

PROCESSING AND PRESERVATION OF CELLS AND PRODUCTS.

16 Cell Harvesting (P Hill and J Bender).

17 Protein Concentration (J Bender).

18 Purification Methods (M Wilson).

19 Virus Safety of Cell-derived Biological Products (PL Roberts).

20 Formulation and Freeze Drying for Lyophilized Biological Medicines (P Matejtschuk and P Phillips).

21 Cell Preservation (R Fleck and B Fuller).

PROPERTIES OF CELL PRODUCTS.

22 Product Characterization from Gene to Therapeutic Product (K Baker, S Flatman and J Birch).

23 Protein Analysis (K Baker and S Flatman).

24 Glycosylation of Medicinal Products (E Tarelli).

25 Immunogenicity of Impurities in Cell-Derived Vaccines (M Duchene, J Descamps and I Pierard).

26 Potency and Safety Assessment of Vaccines and Antitoxins: Use of Cell-based Assays (D Sesardic).

27 Product Stability and Accelerated Degradation Studies (P Matejtschuk and P Phillips).

CELLS AS PRODUCTS.

28 Cell Culture in Tissue Engineering (TE Hardingham, CM Kielty, AE Canfi eld, SR Tew, SG Ball, NJ Turner and KE Ratcliffe).

29 The Use of Stem Cells in Cell Therapy (F Martín, J Jones, P Vaca, G Berná and B Soria).

30 Cells as Vaccines (AG Dalgleish and MA Whelan).

RISK ASSESSMENT AND REGULATORY ASPECTS.

31 Risk Assessment of Cell Culture Procedures (G Stacey).

32 Standardization of Cell Culture Procedures (G Stacey).

33 Good Laboratory Practice for Cell Culture Processing (B Orton).

34 Good Manufacturing Practice for Cell Culture Processing (A Green and G Sharpe).

35 International Regulatory Framework (R Guenther).

36 New Areas: Cell Therapy and Tissue Engineering Products – Technical, Legal and Regulatory Considerations (L Tsang).

Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)