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Doody's Review ServiceReviewer: Giridhar G. Reddy, MD (Rush University Medical Center)
Description: This book on the role of melatonin in psychiatric and neoplastic disorders is edited and written by prominent researchers in their respective fields from universities in the United States and Canada.
Purpose: The purpose is to review the current state of knowledge about the hormone melatonin and its potential role in psychiatric disorders such as depression, sleep and eating disorders, and the possible role of melatonin in neoplastic disorders.
Audience: The primary audience includes adult, child, and adolescent psychiatrists, oncologists, endocrinologists, pediatricians, and other health professionals.
Features: Appropriate figures, graphs, and tables are included to illustrate the text. The article references are extensive and up-to-date.
Assessment: Melatonin is a hormone secreted by the pineal gland. Receptors for melatonin are found not only in the brain but also in cells in other parts of the body. This book reviews the role melatonin plays in psychiatric disorders such as major depression, sleep disorders, chronobiological mood disorders, bipolar disorders, eating disorders, panic disorders, shift-work maladaptation, and jet lag. The possible role of melatonin in neoplastic disorders is also reviewed. Melatonin has been found to have antioxidant properties and thus could play a protective function in cancers of the breast, prostate, and gastrointestinal tract. This book provides a comprehensive update on this topic and is essential reading for all clinicians.