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Membrane Microdomain Signaling: Lipid Rafts in Biology and Medicine / Edition 1
     

Membrane Microdomain Signaling: Lipid Rafts in Biology and Medicine / Edition 1

by Mark P. Mattson
 

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ISBN-10: 1617375152

ISBN-13: 9781617375156

Pub. Date: 11/05/2010

Publisher: Springer-Verlag New York, LLC

Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the

Overview

Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and shows how alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. Techniques are also described for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.

Product Details

ISBN-13:
9781617375156
Publisher:
Springer-Verlag New York, LLC
Publication date:
11/05/2010
Edition description:
Softcover reprint of hardcover 1st ed. 2005
Pages:
214
Product dimensions:
5.98(w) x 9.02(h) x 0.02(d)

Table of Contents

From Intramolecular Asymmetries to Raft Assemblies: A Short Guide for the Puzzled in Lipidomics
Ephraim Yavin and Annette Brand

Regulatory Aspects of Membrane Microdomain (Raft) Dynamics in Live Cells: A Biophysical Approach
János Matkó and János Szöllosi

Lipid Raft Membrane Skeletons
Elizabeth J. Luna, Thomas Nebl, Norio Takizawa, and Jessica L. Crowley

Role of Cholesterol in Membrane Microdomain Signaling
Christopher J. Fielding

Raft Lipid Metabolism in Relation to Alkyl-Lysophospholipid-Induced Apoptosis
Arnold H. van der Luit, Marcel Verheij, and Wim J. van Blitterswijk

Role of Lipid Rafts in Signal Transduction and Synaptic Plasticity of Neural Cells
Markus Delling and Melitta Schachner

Role of Rafts in Virus Fusion and Budding
Wu Ou and Jonathan Silver

Alterations in Raft Lipid Metabolism in Aging and Neurodegenerative Disorders
Mark P. Mattson, Roy G. Cutler, and Norman J. Haughey

Caveolin and Cancer: A Complex Relationship
Mordechai Liscovitch, Elke Burgermeister, Neeru Jain, Dana Ravid, Maria Shatz, and Lilach Tencer

Dietary Modulation of Lipid Rafts: Implications for Disease Prevention and Treatment
Mark P. Mattson

Index

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