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Doody's Review ServiceReviewer: K. P. Ravikrishnan, FRCP (C), FACP (William Beaumont Hospitals)
Description: The Grover Conference, held every other year, is a forum for experts to get together and present their research in the field of pulmonary vascular pathophysiology. This is the proceedings from the September 2008 Grover Conference held in Colorado. The editors provide a good summary of the conference in this publication of the proceedings.
Purpose: The purpose is to present the proceedings of a very important basic science conference.
Audience: The book is clearly intended for clinicians with a special interest in the field of pulmonary circulation. Researchers and basic physiologists will find the proceedings very useful for research technology and advancing their knowledge in the field. For the participants in the conference, the book will be a great resource for a look back into the topics.
Features: The book is divided into chapters with pertinent titles which makes it easy to read and easy for a quick reference. Part I explores the role of channels in modulation of pulmonary vaso-activity and takes readers right away to the advances in the basic understanding of pulmonary vasculature. A thorough yet brief article like the one by Larissa A. Shimoda is an example of this book's use for the clinicians. Her article summarizes the hypoxia-induced channels in the structure and function of the vasculature in chronic pulmonary disease.
Assessment: Clinicians caring for patients with pulmonary hypertension will find this book very useful in understanding the role of channels and transporters in the pathophysiology and the impact of pharmacotherapy in the modulation of pulmonary reactivity. Many chapters delve into basic concepts of pulmonary vascular reactivity and clinicians will find the book extremely helpful in understanding the pathophysiology of the disease they are treating.