Mental and Behavioral Dysfunction in Movement Disorders / Edition 1

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Overview

A state-of-the-art review of the many cognitive, affective, and behavioral dysfunctions associated with movement disorders. These dysfunctions include depression, dementia, psychosis, sleep disorders arising from Parkinson's and Huntington's disease, Tourette's syndrome, as well as multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, and many other related disorders. The authors describe these behavioral syndromes and their neurophysiological and neuropathological substratum, as well as their diagnostic criteria and therapeutic guidelines. The cognitive and affective dysfunctions are spelled out in detail.

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Editorial Reviews

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"An impressive, diverse range of basic science and clinical topics are covered, at least some of which are certain to appeal to every reader...this book has much to offer researchers in this subject." -The Lancet
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Product Details

  • ISBN-13: 9781588291196
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 3/28/2003
  • Edition description: 2003
  • Edition number: 1
  • Pages: 561
  • Product dimensions: 7.02 (w) x 10.48 (h) x 1.24 (d)

Table of Contents

Preface
Contributors
1 Historical Issues in the Study of Behavioral Dysfunction in Movement Disorders 3
2 Fundamental and Clinical Evidence for Basal Ganglia Influences on Cognition 13
3 Integrating Cognition and Motivation into the Basal Ganglia Pathways of Action 35
4 Understanding Corticobasal Ganglia Networks as Part of a Habit Formation System 51
5 The Role of the Cerebellum in Cognition and Emotion 59
6 Assessing Cognition in Movement Disorders 85
7 Disorders of Intention in Parkinsonian Syndromes 101
8 Cognitive Control in Frontostriatal Disorders 113
9 Disorders of Speech and Language in Parkinson's Disease 125
10 Distinctive Features of Apraxia in Corticobasal Degeneration and Other Neurological Illnesses 135
11 Neuropsychological Deficits in Cerebellar Syndromes 147
12 Induction and Reversal of Cognitive Deficits in a Primate Model of Huntington's Disease 159
13 Induction and Reversal of Cognitive Deficits in a Primate Model of Parkinson's Disease 173
14 Catecholamines and Cognition: Bridging the Gap Between Animal Studies and Clinical Syndromes 183
15 Nondopaminergic Influences on Cognition in Parkinson's Disease 201
16 Cognitive Consequences of Neurosurgery for Parkinson's Disease 211
17 The Clinical Spectrum of Dementia in Movement Disorders: An Overview 223
18 Neuropathological Distinctions and Similarities in Movement Disorders with Dementia 231
19 Homologies Between the Genetic Etiology and Pathogenesis of the Synucleinopathies and Tauopathies 255
20 Prevalence, Incidence, and Risk Factors for Dementia in Parkinson's Disease 259
21 Neuropsychiatric Co-Morbidity in Dementia With and Without Movement Disorders 271
22 Neurotransmitter Correlates of Neuropsychiatric Symptoms in Dementia with Lewy Bodies 285
23 Acetylcholinesterase Inhibitors in the Treatment of Dementia in Parkinson's Disease 295
24 Mood Disorders and the Globus Pallidus 305
25 Cortical-Limbic-Striatal Dysfunction in Depression: Converging Findings in Basal Ganglia Diseases and Primary Affective Disorders 321
26 Agitation and Apathy in Hyper- and Hypokinetic Movement Disorders 339
27 Diagnosis and Treatment of Depression in Parkinson's Disease 351
28 Diagnosis and Treatment of Hallucinations and Delusions in Parkinson's Disease 369
29 REM Sleep Behavior Disorder in Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy 383
30 Psychogenic Parkinsonism and Dystonia 399
31 Clinical Management of Psychosis and Mood Disorders in Huntington's Disease 409
32 Clinical Management of Aggression and Frontal Symptoms in Huntington's Disease
33 Heterogeneous Psychopathology of Tourette Syndrome 443
34 In Search of the Pathophysiology of Tourette Syndrome 467
35 Obsessive-Compulsive Disorder as a Frontostriatal-Thalamic Dysfunction 477
36 Dyskinesia in Patients with Schizophrenia Never Treated with Antipsychotics: Conceptual and Pathophysiological Implications 489
37 Medical and Psychosocial Determinants of Quality of Life in Parkinson's Disease 501
38 Sexuality and Parkinson's Disease 517
39 Daytime Sleepiness and Sleep Attacks in Idiopathic Parkinson's Disease 527
40 Natural Evolution and Life Expectancy in Parkinson's Disease 539
Index 545
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