Mental and Behavioral Dysfunction in Movement Disorders / Edition 1

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In addition to movement per se, movement disorders affect multiple mental processes and complex behavioral functions, and so must be taken into careful account when clinically managing a wide variety of behavioral problems. In Mental and Behavioral Dysfunction in Movement Disorders, internationally renowned researchers and clinicians review the many recent developments in the field, both to shed light on and to establish new standards for the study and treatment of the multiple cognitive, affective, and behavioral dysfunctions associated with movement disorders. These dysfunctions include depression, dementia, psychosis, sleep disorders arising from Parkinson's and Huntington's diseases, and Tourette syndrome, as well as multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, and many other related disorders. The authors describe these behavioral syndromes and their neurophysiological and neuropathological substratum, as well as their diagnostic criteria and therapeutic guidelines. For each syndrome, the cognitive deficits of attention, memory, language, praxis, and executive functions are spelled out in detail. Also discussed are the neuropsychiatry of movement disorders and the quality of life issues associated with Parkinson's disease. Exhaustive and cutting-edge, Mental and Behavioral Dysfunction in Movement Disorders illuminates the many complex mental and behavioral conditions associated with these disorders, and constitutes an essential guide for all physicians treating these problems or scientists studying these topics today.
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Editorial Reviews

From the Publisher
"An impressive, diverse range of basic science and clinical topics are covered, at least some of which are certain to appeal to every reader...this book has much to offer researchers in this subject." -The Lancet
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Product Details

  • ISBN-13: 9781617373725
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 11/5/2010
  • Edition description: Softcover reprint of hardcover 1st ed. 2003
  • Edition number: 1
  • Pages: 561
  • Product dimensions: 10.00 (w) x 7.00 (h) x 1.17 (d)

Table of Contents

I. Introduction

Historical Issues in the Study of Behavioral Dysfunction in Movement Disorders

Christopher G. Goetz

II. Mental Processing in the Motor Structures of the Brain

Fundamental and Clinical Evidence for Basal Ganglia Influences on Cognition

Frank A. Middleton

Integrating Cognition and Motivation into the Basal Ganglia Pathways of Action

Suzanne N. Haber

Understanding Corticobasal Ganglia Networks as Part of a Habit Formation System

Ann M. Graybiel and Yasuo Kubota

The Role of the Cerebellum in Cognition and Emotion

Jeremy D. Schmahmann

III. Cognition in Movement Disorders

Assessing Cognition in Movement Disorders

Julie C. Stout and Jane S. Paulsen

Disorders of Intention in Parkinsonian Syndromes

Richard G. Brown

Cognitive Control in Frontostriatal Disorders

Francois Richer and Sylvain Chouinard

Disorders of Speech and Language in Parkinson's Disease

Henri Cohen

Distinctive Features of Apraxia in Corticobasal Degeneration and Other Neurological Illnesses

Ramón Leiguarda

Neuropsychological Deficits in Cerebellar Syndromes

Hermann Ackermann and Irene Daum

IV. Neurophysiology of Cognition in Movement Disorders

Induction and Reversal of Cognitive Deficits in a Primate Model of Huntington's Disease

Stéphane Palfi, Emmanuel Brouillet, Françoise Condé, and Philippe Hantraye

Induction and Reversal of Cognitive Deficits in a Primate Model of Parkinson's Disease

Jay S. Schneider

Catecholamines and Cognition: Bridging the Gap Between Animal Studies and Clinical Syndromes

Trevor W. Robbins, Harriet S. Crofts, Roshan Cools, and Angela C. Roberts

Nondopaminergic Influences on Cognition in Parkinson's Disease

Marc-André Bédard, Maxime Lévesque, Simon Lemay, and François Paquet

Cognitive Consequences of Neurosurgery for Parkinson's Disease

Jean A. Saint-Cyr

V. Dementia in Movement Disorders

The Clinical Spectrum of Dementia in Movement Disorders: An Overview

Andrew Kertesz

Neuropathological Distinctions and Similarities in Movement Disorders with Dementia

Kurt A. Jellinger

Homologies Between the Genetic Etiology and Pathogenesis of the Synucleinopathies and Tauopathies

John Hardy

Prevalence, Incidence, and Risk Factors for Dementia in Parkinson's Disease

Gilberto Levy and Karen Marder

Neuropsychiatric Co-Morbidity in Dementia With and Without Movement Disorders

Clive G. Ballard and Alan Thomas.

Neurotransmitter Correlates of Neuropsychiatric Symptoms in Dementia with Lewy Bodies

Elaine K. Perry, Margaret A. Piggott, Mary Johnson, Clive G. Ballard, Ian G. McKeith, Robert Perry, and David Burn

Acetylcholinesterase Inhibitors in the Treatment of Dementia in Parkinson's Disease

Amos D. Korczyn and Nir Giladi

VI. Neuropsychiatric Aspects of Movement Disorders

Mood Disorders and the Globus Pallidus

Edward C. Lauterbach

Cortical-Limbic-Striatal Dysfunction in Depression: Converging Findings in Basal Ganglia Diseases and Primary Affective Disorders

Taresa L. Stefurak and Helen S. Mayberg

Agitation and Apathy in Hyper- and Hypokinetic Movement Disorders

Irene Litvan and Jaime Kulisevsky

Diagnosis and Treatment of Depression in Parkinson's Disease

Vladimir S. Kostíc, Elka Stefanova, Nataþsa Dragaþsevíc, and Saþska Potrebíc

Diagnosis and Treatment of Hallucinations and Delusions in Parkinson's Disease

Dag Aarsland and Jan Petter Larsen

REM Sleep Behavior Disorder in Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy

Bradley F. Boeve, Michael H. Silber, Tanis J. Ferman, Joseph E. Parisi, Dennis W. Dickson, Glenn E. Smith, John Lucas, and Ronald C. Petersen

Psychogenic Parkinsonism and Dystonia

Daniel S. Sa and Anthony E. Lang

Clinical Management of Psychosis and Mood Disorders in Huntington's Disease

Mark Guttman, Meneske Alpay, Sylvain Chouinard, Peter Como, Anthony Feinstein, Ira Leroi, and Adam Rosenblatt

Clinical Management of Aggression and Frontal Symptoms in Huntington's Disease

Adam Rosenblatt, Karen Anderson, Alex D. Goumeniouk, Paul Lespérance, Martha A. Nance, Jane S. Paulsen, Allen Rubin, Jean A. Saint-Cyr, Russ Sethna, and Mark Guttman

Heterogeneous Psychopathology of Tourette Syndrome

Mary M. Robertson

In Search of the Pathophysiology of Tourette Syndrome

James F. Leckman

Obsessive-Compulsive Disorder as a Frontostriatal-Thalamic Dysfunction

Tiffany R. Farchione, Shauna N. MacMillan, and David R. Rosenberg

Dyskinesia in Patients with Schizophrenia Never Treated with Antipsychotics: Conceptual and Pathophysiological Implications

Christian Bocti, Deborah N. Black, and John L. Waddington

VII. Quality of Life in Parkinson's Disease

Medical and Psychosocial Determinants of Quality of Life in Parkinson's Disease

Anette Schrag and Caroline Selai

Sexuality and Parkinson's Disease

Gila Bronner, Vladimir Royter, Amos D. Korczyn, and Nir Giladi

Daytime Sleepiness and Sleep Attacks in Idiopathic Parkinson's Disease

David B. Rye, Joseph T. Daley, Amanda A. Freeman, and Donald L. Bliwise

Natural Evolution and Life Expectancy in Parkinson's Disease

Werner Poewe


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