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From The CriticsReviewer: Matthew J Sorrentino, MD (University of Chicago Pritzker School of Medicine)
Description: This book addresses the definition of the metabolic syndrome, discusses the association of metabolic syndrome with vascular disease and diabetes, and reviews treatment approaches to the major components of the syndrome. It carefully reviews the clinical literature and current preventive treatment guidelines.
Purpose: The purpose is to present a scientific account of the features of the metabolic syndrome to a clinically oriented audience. Multiple definitions and confusion regarding the designation of a "syndrome" make clarification of this vastly growing area of research timely and important. The editors have met this objective with an excellent summary of the history of metabolic syndrome in an introduction by Scott Grundy that clarifies the current understanding of the components of the syndrome and the utility of identifying patients with this syndrome.
Audience: The book is written for clinicians who treat patients with the metabolic syndrome and is particularly useful to primary care physicians, endocrinologists, cardiologists, and allied health professionals involved in preventive medicine. It will be useful to anyone who wishes to understand the clinical studies underlying our current understanding of the syndrome. Andrew J. Krentz is a consultant in diabetes at Southampton General Hospital in the U.K. and contributes a strong chapter on the role of the metabolic syndrome and insulin resistance on vascular disease. Nathan D. Wong is the Director of the Heart Disease Prevention Program at the University of California Irvine and writes an excellent overview of the epidemiology of the metabolic syndrome.
Features: Definitions, diagnosis and epidemiology of the metabolic syndrome are thoroughly covered. The book addresses the link between the metabolic syndrome, vascular disease and diabetes. Approaches to glycemic control, treatment of dyslipidemia, hypertension, and obesity are outlined with a focus on lifestyle changes and patient compliance. All the recommendations are supported by a careful review of the current medical literature. Missing is a comprehensive review of the role of the adipocyte. An overview of the clinical studies addressing lifestyle treatment is included, but a practical guide to popular diets would have been a useful addition.
Assessment: This excellent book clarifies the controversy about the usefulness of the metabolic syndrome in clinical practice. It is a timely review of what has become a common and potentially devastating clustering of risk factors in a large number of people. The book gives good general recommendations for treatment based on currently accepted guidelines.