Metabolic Syndrome and Cardiovascular Disease

Overview

Addressing a topic of utmost importance in the field, this text addresses the epidemiology, diagnosis, assessment, and management of patients with metabolic syndrome-focusing on implications for cardiovascular disease risk. With an abundance of clearly organized tables, flowcharts, and practice guidelines, this blue-ribbon source succinctly analyzes recent clinical trials, compares and assesses recent and emerging therapies, and provides recommendations for the improved assessment and treatment of patients, while...

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Overview

Addressing a topic of utmost importance in the field, this text addresses the epidemiology, diagnosis, assessment, and management of patients with metabolic syndrome-focusing on implications for cardiovascular disease risk. With an abundance of clearly organized tables, flowcharts, and practice guidelines, this blue-ribbon source succinctly analyzes recent clinical trials, compares and assesses recent and emerging therapies, and provides recommendations for the improved assessment and treatment of patients, while supplying a state-of-the-art overview of approaches to optimize and enhance patient care.

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Editorial Reviews

Doody's Review Service
Reviewer: Matthew J Sorrentino, MD (University of Chicago Pritzker School of Medicine)
Description: This book addresses the definition of the metabolic syndrome, discusses the association of metabolic syndrome with vascular disease and diabetes, and reviews treatment approaches to the major components of the syndrome. It carefully reviews the clinical literature and current preventive treatment guidelines.
Purpose: The purpose is to present a scientific account of the features of the metabolic syndrome to a clinically oriented audience. Multiple definitions and confusion regarding the designation of a "syndrome" make clarification of this vastly growing area of research timely and important. The editors have met this objective with an excellent summary of the history of metabolic syndrome in an introduction by Scott Grundy that clarifies the current understanding of the components of the syndrome and the utility of identifying patients with this syndrome.
Audience: The book is written for clinicians who treat patients with the metabolic syndrome and is particularly useful to primary care physicians, endocrinologists, cardiologists, and allied health professionals involved in preventive medicine. It will be useful to anyone who wishes to understand the clinical studies underlying our current understanding of the syndrome. Andrew J. Krentz is a consultant in diabetes at Southampton General Hospital in the U.K. and contributes a strong chapter on the role of the metabolic syndrome and insulin resistance on vascular disease. Nathan D. Wong is the Director of the Heart Disease Prevention Program at the University of California Irvine and writes an excellent overview of the epidemiology of the metabolic syndrome.
Features: Definitions, diagnosis and epidemiology of the metabolic syndrome are thoroughly covered. The book addresses the link between the metabolic syndrome, vascular disease and diabetes. Approaches to glycemic control, treatment of dyslipidemia, hypertension, and obesity are outlined with a focus on lifestyle changes and patient compliance. All the recommendations are supported by a careful review of the current medical literature. Missing is a comprehensive review of the role of the adipocyte. An overview of the clinical studies addressing lifestyle treatment is included, but a practical guide to popular diets would have been a useful addition.
Assessment: This excellent book clarifies the controversy about the usefulness of the metabolic syndrome in clinical practice. It is a timely review of what has become a common and potentially devastating clustering of risk factors in a large number of people. The book gives good general recommendations for treatment based on currently accepted guidelines.
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Product Details

  • ISBN-13: 9780849393730
  • Publisher: CRC Press
  • Publication date: 11/6/2006
  • Pages: 344
  • Product dimensions: 6.10 (w) x 9.10 (h) x 0.90 (d)

Table of Contents


Preface     v
Acknowledgments     vii
Contributors     xi
Introduction   Scott M. Grundy     xiii
Metabolic Syndrome: Nomenclature, Definition, and Diagnosis   K. George M. Alberti   Paul Z. Zimmet     1
Epidemiology and Cardiovascular Disease Risk Assessment in the Metabolic Syndrome   Nathan D. Wong     17
Metabolic Syndrome and Type 2 Diabetes Mellitus   Ali Jawa   Vivian Fonseca     41
Vascular Biology of the Metabolic Syndrome   Justin M. S. Lee   Robin P. Choudhury     79
Vascular Disease in the Metabolic Syndrome: Mechanisms and Consequences   Andrew J. Krentz   Sarah Wild   Christopher D. Byrne     109
Glycemic Control and the Metabolic Syndrome   John E. Gerich   Regina Dodis     145
Dyslipidemia in the Metabolic Syndrome   Natalia B. Volkova   Prakash C. Deedwania     191
Hypertension in the Metabolic Syndrome   Stanley S. Franklin     219
Obesity, Physical Activity, and Nutrition in the Metabolic Syndrome   Gang Hu   Timo A. Lakka   Hanna-Maaria Lakka   Jaakko Tuomilehto     241
Management of Patients with the MetabolicSyndrome: Compliance with or Adherence to Treatment?   C. Tissa Kappagoda   Ezra A. Amsterdam     279
Index     307
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