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From The CriticsReviewer: Ronald N. Cohen, MD (University of Chicago Medical Center)
Description: This pocket-sized manual covers all aspects of the metabolic syndrome and related disorders, including diabetes, cardiovascular disease, and polycystic ovary syndrome.
Purpose: This is a concise and practical guide to the diagnosis, evaluation, treatment, and prevention of the metabolic syndrome. Since the incidence of the metabolic syndrome is rising rapidly and the disorder is associated with significant cardiovascular and other morbidities, this is a very worthwhile objective. Although a concise manual on this topic is very welcome, this one has some limitations. For instance, there are no references and, although the authors support the use of thiazolidinediones for many aspects of treatment, they should also highlight the potential problems with their use.
Audience: The manual is written for primary care physicians, cardiologists, endocrinologists, and residents. The authors are very knowledgeable, and the book is written at the appropriate level.
Features: After a general discussion of the metabolic syndrome, the authors discuss the cardiovascular outcomes of treating this disorder. Next, the relationship between diabetes and the metabolic syndrome is defined. The effects of metabolic syndrome on various organs are reviewed, including the liver, genitourinary, central nervous system, and lungs. An interesting chapter discusses the risk of malignancy in patients with metabolic syndrome. Although it is well written, this book would have benefited from some references, particularly since it covers a variety of controversial topics. In addition, there is a heavy emphasis on the use of thiazolidinediones and, although they are noted to improve cardiac risk factors and metabolic outcomes, the book does not discuss in detail the potential role of rosiglitazone in cardiac events.
Assessment: This is an interesting book on various aspects of the metabolic syndrome. Although it might benefit from references and additional viewpoints, it is a focused, well-written discussion of an important metabolic disorder.