Metals and Oxidative Damage in Neurological Disorders / Edition 1

Metals and Oxidative Damage in Neurological Disorders / Edition 1

by James R. Connor
     
 

ISBN-10: 030645534X

ISBN-13: 9780306455346

Pub. Date: 09/30/1997

Publisher: Springer US

This volume brings together scientists and clinicians from diverse disciplines for discussions of oxidative injury in the nervous system. Areas of examination include:

• a review of metals and their role in oxidative injury, with special attention paid to iron
• the mechanisms by which the brain protects itself from oxidative harm

…  See more details below

Overview

This volume brings together scientists and clinicians from diverse disciplines for discussions of oxidative injury in the nervous system. Areas of examination include:

• a review of metals and their role in oxidative injury, with special attention paid to iron
• the mechanisms by which the brain protects itself from oxidative harm
• the clinical diseases in which oxidative injury is known to contribute to the pathogenic process
• antioxidant therapeutic strategies in neurological disorders, and
• a proposed common pathway for oxidative injury in the brain.

Product Details

ISBN-13:
9780306455346
Publisher:
Springer US
Publication date:
09/30/1997
Edition description:
1997
Pages:
374
Product dimensions:
7.01(w) x 10.00(h) x 0.04(d)

Table of Contents

Ch. 1Iron and Neurotransmitter Function in the Brain
Ch. 2Evidence for Iron Mismanagement in the Brain in Neurological Disorders
Ch. 3Magnetic Resonance Imaging of Brain Iron
Ch. 4Neurochemical Roles of Copper as Antioxidant or Prooxidant
Ch. 5Manganese Neurotoxicity and Oxidative Damage
Ch. 6The Role of Zinc in Brain and Nerve Functions
Ch. 7Delivery of Metals to Brain and the Role of the Blood-Brain Barrier
Ch. 8Ferritin: Intracellular Regulator of Metal Availability
Ch. 9Ascorbate: An Antioxidant Neuroprotectant and Extracellular Neuromodulator
Ch. 10Vitamin E: Neurochemical Aspects and Relevance to Nervous System Disorders
Ch. 11Nitric Oxide and Oxidative Damage in the CNS
Ch. 12Iron and Oxidative Stress in Neonatal Hypoxic-Ischemic Brain Injury: Directions for Therapeutic Intervention
Ch. 13The Role of Oxidative Processes and Metal Ions in Aging and Alzheimer's Disease
Ch. 14Oxidative Stress with Emphasis on the Role of LAMMA in Parkinson's Disease
Ch. 15Perspectives on the Mechanisms of Familial Amyotrophic Lateral Sclerosis Caused by Mutations in Superoxide Dismutase 1
Ch. 16Tardive Dyskinesia and Oxidative Stress
Ch. 17Antioxidant Therapeutic Strategies in CNS Disorders
Ch. 18Oxidative Stress-Induced Cell Damage in the CNS: A Proposal for a Final Common Pathway
AppendixAccepted Biomarkers of Oxidative Damage in Tissues
Index

Read More

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >