Methods For Neural Ensemble Recordings / Edition 1

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Overview

Neuroscientists have long recognized the importance of understanding the underlying principles of information processing by large populations of neurons. Methods for Neural Ensemble Recordings explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. Since current methods allow one to simultaneously record the extracellular activity of up to 100-150 neurons for days or even weeks, neural ensemble recordings have been used to address long-standing issues in development, learning, memory, sensorimotor integration, sensory information processing, and neuronal plasticity.

EXAMINES THE MANY POSSIBLE APPLICATIONS FOR THIS REVOLUTIONARY METHOD

Each chapter offers a step-by-step description for the implementation of a particular technique or experimental paradigm employing simultaneous multiple electrode recordings. The techniques described can be used in applications that impact a large group of life scientists, including:

  • drug screening (pharmacology) in both in vitro and in vivo preparations
  • developmental studies and studies of neuronal plasticity
  • chronic monitoring of neuronal function in behavioral studies
  • physiological monitoring of neuronal activity in cell cultures and brain slices
  • physiological monitoring of neuronal activity in neurons trafected with genetic vectors
  • chronic monitoring of physiological changes in populations of neurons during learning of new sensorimotor and cognitive tasks

Disc. electrode recording techniques used to record informa- tion processing activities in animal brains.

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Editorial Reviews

Booknews
Explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. Addresses the application of these techniques to issues in development, learning, memory, sensory information processing, sensorimotor integration, and neuronal plasticity. The 11 chapters present both research results and state-of-the-art methods in this emerging field. Annotation c. by Book News, Inc., Portland, Or.
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Product Details

Table of Contents

Electrodes for Many Single Neural Recordings, E. Schmidt Multi-Channel Electrode Design: Considerations for Different Applications, K.A. Moxon Trends in Multichannel Neural Ensemble Recording Instrumentation, K. Sameshima and L.A. Baccala Automatic Discrimination of Single Units, B.C. Wheeler Acute in vivo Multielectrode Recording from the Cerebellum, J.P. Welsh and Cornelius Schwarz Methods for Chronic Neural Ensemble Recordings in Singing Birds, A.S. Dave, A.C. Yu, J.J. Gilpin, and D. Margoliash Methods for Simultaneous Multisite Neural Ensemble Recordings in Behaving Primates, M.A.L. Nicolelis, C.R. Stambaugh, A. Brisben, and M. Laubach Correlations Based Analysis Methods for Neural Ensemble Data, G.L. Gerstein Directed Coherence: A Tool for Exploring Functional Interactions among Brain Structures, L.A. Baccala and K. Sameshima Using Multivariate Statistical Methods to Analyze Multi-Single Neuron Recording Data, J.K. Chapin Pitfalls and Problems in the Analysis of Neural Ensemble Recordings during Behavioral Tasks, R.E. Hampson and S.A. Deadwyler

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