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Doody's Review ServiceReviewer: Patrick J McDonnell, Pharm.D.(Temple University School of Pharmacy)
Description: This encyclopedia is an extremely comprehensive compendium of the adverse effects of drugs, classifying these effects in an organ specific approach. Pertinent drug interactions are also featured. This is an update of a 2000 edition.
Purpose: The phrase "primum non nocere" or do no harm appears in the foreword. The reality of drug induced disease has certainly come to light with much effort and attention being placed on drug safety. With this encyclopedia, the practitioner is able to ascertain whether a patient's condition is iatrogenic/drug induced or idiopathic or, better yet, able to identify patients at risk for iatrogenic drug injury and develop strategies to prevent these events.
Audience: The audience certainly could include any professional who deals with the prescription or verification of medications (physicians/pharmacists/nurses), and the publication certainly would be worthwhile for those who study in the realm of pharmacoepidemiology. The editors and contributors include nearly 200 experts in their respective pharmacotherapy fields.
Features: The format has changed with this edition, which uses a monograph structure that features an individual drug or drug class. Previous editions used a chapter structure, mainly in the realm of organ specific adverse drug events. The monographs in this edition provide among the most complete explanations of a drug's particular adverse effects, covering the mechanism of the event, reported incidence, patient populations at risk, management of the event occurrence, to name just a few highlights. A complete index lists the drugs associated with a particular adverse effect, which of course refers the user to a particular monograph.
Assessment: As a pharmacy instructor and consultant in the area of drug induced disease, I am extremely impressed with the content and layout of this encyclopedia. It is one of the most complete yet user friendly publications on these disease states. It would be a worthwhile addition to medical, pharmacy, and other allied health school libraries.