Microalbuminuria: Biochemistry, Epidemiology and Clinical Practice / Edition 1

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Overview

Microalbuminuria, the abnormal urinary excretion of albumin, is recognized as an important independent marker of both renal and cardiovascular disease, particularly in diabetes mellitus. This volume is the only comprehensive and up-to-date review of the relevance of microalbuminuria to health and disease. It covers the pathophysiology and epidemiology of microalbuminuria and the methodology of laboratory assessment, and discusses the nonspecific nature of microalbuminuria in less well-recognized clinical situations. This is the first book to deal in detail with the treatment of microalbuminuria in both diabetic and nondiabetic subjects. This volume will be an essential source of reference and a guide to clinical practice for diabetologists, endocrinologists, cardiologists, renal physicians, and clinical biochemists.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Patrick Cunningham, MD (University of Chicago Hospitals)
Description: This book discusses microalbuminuria in diabetes and nondiabetic disorders, especially with regard to its role in prognosis and complications.
Purpose: The authors aim to summarize the vast literature on microalbuminuria in diabetes and nondiabetic disorders.
Audience: It is intended for those studying diabetes and its complications. As the authors imply, the audience is mainly serious academicians.
Features: This book covers the measurement and definition of microalbuminuria, various confounding factors which influence it, its natural history in diabetes, its association with cardiovascular disease and a possible biologic mechanism for this, and its role in patient management. Its relevance in non-diabetes is a worthy point, and discussion of its measurement and definition is succinct and helpful. However, the longest chapter, which details the associations between microalbuminuria and cardiovascular risk factors, is confusing. Because this area is inherently complicated, the exhaustive regurgitation of this data without sufficient summarization or explanation is tedious. Those without a thorough knowledge of lipid epidemiology have no hope of following parts of this discussion.
Assessment: Although this book addresses a quite relevant subject, its readability is limited by the authors' excessive focus on epidemiologic associations out of proportion to the question of causality or biologic mechanism. This book would benefit from more author opinion and specific management recommendations in the attempt to generate some consensus.
Patrick Cunningham
This book discusses microalbuminuria in diabetes and nondiabetic disorders, especially with regard to its role in prognosis and complications. The authors aim to summarize the vast literature on microalbuminuria in diabetes and nondiabetic disorders. It is intended for those studying diabetes and its complications. As the authors imply, the audience is mainly serious academicians. This book covers the measurement and definition of microalbuminuria, various confounding factors which influence it, its natural history in diabetes, its association with cardiovascular disease and a possible biologic mechanism for this, and its role in patient management. Its relevance in non-diabetes is a worthy point, and discussion of its measurement and definition is succinct and helpful. However, the longest chapter, which details the associations between microalbuminuria and cardiovascular risk factors, is confusing. Because this area is inherently complicated, the exhaustive regurgitation of this data without sufficient summarization or explanation is tedious. Those without a thorough knowledge of lipid epidemiology have no hope of following parts of this discussion. Although this book addresses a quite relevant subject, its readability is limited by the authors' excessive focus on epidemiologic associations out of proportion to the question of causality or biologic mechanism. This book would benefit from more author opinion and specific management recommendations in the attempt to generate some consensus.

2 Stars from Doody
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Product Details

  • ISBN-13: 9780521457033
  • Publisher: Cambridge University Press
  • Publication date: 10/28/1998
  • Edition number: 1
  • Pages: 250
  • Product dimensions: 6.85 (w) x 9.72 (h) x 0.59 (d)

Table of Contents

Foreword Professor K. G. M. M. Alberti; 1. Renal structure and physiology; 2. Measurement and expression of microalbuminuria; 3. Epidemiolgy and determinants of microalbuminuria in health; 4. Epidemiolgy and determinants of microalbuminuria in diabetes mellitus; 5. Microalbuminuria as a marker of endothelial dysfunction; 6. Microalbuminuria, cardiovascular risk factors and cardiovascular disease; 7. Microalbuminuria as a non-specific marker of disease; 8. Management of microalbuminuria in diabetes mellitus and essential hypertension; Index.

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