Microbe / Edition 1

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An exciting introduction to the world of microbes
• Covers the most pertinent information related to the study of microbes, including microbial activity; structure and function; growth, inheritance, physiology, and diversity; and biological interactions
• Engages students in the learning process with a clear style and unique perspective
• Serves as a textbook for upper level undergraduate courses in general microbiology.
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Product Details

  • ISBN-13: 9781555813208
  • Publisher: ASM Press
  • Publication date: 1/28/2006
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 558
  • Sales rank: 925,324
  • Product dimensions: 8.40 (w) x 10.70 (h) x 1.00 (d)

Table of Contents

Table of Contents


About the Authors

Study Aids

Section I. Microbial Activity

1. The World of Microbes

· Introduction

· What is a microbe?

· Having a long past

· Being small

· Being many

· Growing and persisting

· Colonizing every niche and making Earth inhabitable

· Shaping the planet

· Making a living

· Cooperating for complex endeavors

· Conclusions

· Study questions

Section II. Structure and Function

2. Prokaryotic Cell Structure and Function: Envelopes and Appendages

· Prokaryotic cells

· Microscopes

o Newer microscopes

§ Scanned-proximity probe microscopes

§ Molecular stains

· Prokaryotes have complex envelopes and appendages

· The cell membrane

· How the cell membrane is protected

o The gram-positive solution

o The gram-negative solution

o The acid-fast solution

o Crystalline surface layers

o Bacteria without cell walls: the mycoplasmas

o Cell envelopes of the Archaea

· Capsules, flagella, and pili: how prokaryotes cope in certain environments

o Capsules and slime layers

o Flagella

o Pili

· Study questions

3. Prokaryotic Cell Structure and Function: the Cell Interior

· General observations

· The nucleoid

· The cytoplasm

· Inclusions and vesicles

o Gas vesicles

o Organelles for photosynthesis and chemosynthesis

o Carboxysomes

o Enterosomes

o Storage granules and others

· Conclusions

· Study questions

Section III. Growth

4. Growth of Microbial Populations

· Introduction

· How to measure growth of a bacterial culture

· When should the growth rate be determined?

· The law of growth

· Balanced growth

· Continuous culture

· How is the physiology of the cells affected by the growth rate?

· Effects of temperature, hydrostatic pressure, osmotic strength, and pH

o Temperature

§ Effect on growth rate

§ Classifying the temperature responses of microbes

§ Growth limits at temperature extremes

§ Lethal effects

o Hydrostatic pressure

o Osmotic pressure

o pH

· Conclusions

· Study questions

5. Making a Cell

· Introduction

· Growth metabolism: making life from nonlife

· Framework of growth metabolism

o Making two from one

o Assembling cell structures

o Making macromolecules

o Synthesizing building blocks

o Fueling

· Global effects of growth metabolism

o Earth’s chemical cycles

o Bioremediation

· Summary and plan

· Study questions

6. Fueling

· Overview of fueling reactions

· Getting energy and reducing power

o Driving force and its generation

o Substrate level phosphorylation and fermentation

o Transmembrane ion gradients

§ Respiration

§ Photosynthesis

§ Enzyme pumps

§ Scalar reactions

o Oxygen and life

· Making precursor metabolites: heterotrophy

o Acquiring nutrients

§ Transport through the OM of gram-negative bacteria

§ Transport through the cell membrane

o Feeder pathways

o Central metabolism

§ Common pathways of central metabolism

§ Auxiliary pathways of central metabolism

§ Diversity and flexibility of central metabolism

· Making precursor metabolites: autotrophy

o The Calvin cycle

o Other CO2-fixing cycles

· Summary

· Study questions

7. Biosynthesis

· Some general observations

o Biosynthesis and nutrition

o Bacterial studies and biosynthetic pathways

o The concept of a biosynthetic pathway

· Assimilation of nitrogen

o Central actors: glutamate and glutamine

o Synthesis of glutamate and glutamine

o Getting ammonia

o Ammonia from dinitrogen

· Assimilation of sulfur

· Assimilation of phosphorus

· Pathways to building blocks

o Amino acids

o Nucleotides

o Sugars and sugar-like derivatives

o Fatty acids and lipids

· Summary

· Study questions

8. Building Macromolecules

· Introduction


o Overview of replication

o Initiation of replication

o DNA strand elongation

o Repair of errors in replication

o Termination of replication

o Protecting the DNA

o Assembly of the nucleoid


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