Microbial Subversion of Host Cells

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Microbes have co-evolved over time with other organisms to the extent that some are so acquainted with host cell biology that they subvert key cellular processes with unrivalled precision. This volume reviews this exciting new discipline, reflecting the recent explosion of knowledge as well as broader insights into fundamental cellular processes. C. David O'Connor and David Smith cover the salient aspects by using a range of model systems.

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Editorial Reviews

From the Publisher
'... a tremendous book, full of well-presented up-to-date information covering a wide range of subjects related to cellular microbiology.' Microbiology Today

'There is something here for everybody, students will find inspiration and sources of information for essays, lecturers will find the figures particularly useful and researchers working in the fields of both microbiology and cell biology will find something new and of interest.' Institute of Biology

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Product Details

Meet the Author

David O'Connor is Professor of Molecular Microbiology and Director of the Centre for Proteomic Research at the University of Southampton, UK.

David Smith is a Senior Lecturer in the Division of Veterinary Pathology at the University of Edinburgh, UK.

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Table of Contents

Preface; 1. The structure of the enteropathogenic Escherichia coli type III-secretion apparatus Elizabeth A. Creasey and Gad Frankel; 2. Vaccinia virus movement in cells Geoffrey L. Smith; 3. Induction of pro-inflammatory signals by Salmonella-epithelial cell interactions Abigail N. Blakey and Edouard E. Galyov; 4. Modulation of Toll-like receptor signalling by viruses Andrew Bowie; 5. Enteropathogenic Escherichia coli (EPEC) and its effector molecules Brendan Kenny and Jonathan Warawa; 6. Lipid-protein interactions in enveloped virus entry, protein traffic, and assembly Min Li, Andrei N. Vzorov, Armin Weidmann, Chinglai Yang and Richard W. Compans; 7. Legionella pneumophila: a model system to study bacterial modulation of phagosome transport Craig R. Roy; 8. Regulation of membrane fusion processes in eukaryotic cells: what can we learn from pathogenic mycobacteria? Jean Pieters; 9. Molecular and cellular mechanisms of action of the VacA and HP-NAP virulence factors of Helicobacter pylori Marina de Bernard and Cesare Montecucco; 10. Who is controlling the inflammatory response in shigellosis - bacteria or host? Jonathan D. Edgeworth and Philippe J. Sansonetti; 11. Cell death on demand: herpes simplex viruses and apoptosis Joshua Munger, Guoying Zhou and Bernard Roizman; 12. Apoptosis in Shigella and Salmonella infections Volker Brinkmann and Arturo Zychlinsky; 13. Setting up a nest and maintaining it: intracellular replication of Legionella pneumophila Ralph R. Isberg; 14. Entry of Listeria monocytogenes into mammalian cells: from cell biology to physiopathology P. Cossart; Index.

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