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Microbiological Assay for Pharmaceutical Analysis: A Rational Approach [NOOK Book]

Overview

A user-friendly guide for the evaluation of microbiological assays, Microbiological Assay for Pharmaceutical Analysis: A Rational Approach provides a lucid explanation of the sources of error in microbiological assay and helps analysts choose efficient assay designs that will minimize those sources of error. Beginning with a review of the theoretical basis for the quantitative aspects, the author discusses microbiological assay as a branch of pharmaceutical analysis and distinguishes it from biological assay in ...
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Microbiological Assay for Pharmaceutical Analysis: A Rational Approach

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Overview

A user-friendly guide for the evaluation of microbiological assays, Microbiological Assay for Pharmaceutical Analysis: A Rational Approach provides a lucid explanation of the sources of error in microbiological assay and helps analysts choose efficient assay designs that will minimize those sources of error. Beginning with a review of the theoretical basis for the quantitative aspects, the author discusses microbiological assay as a branch of pharmaceutical analysis and distinguishes it from biological assay in general. He draws attention to the microbiological aspects that may not be so obvious to the chemical analyst and to the analytical aspects that may not be so obvious to the microbiologist.

The book contains detailed evaluations of assays that illustrate typical experimental designs and addresses how to present a realistic assessment of the best potency estimate from a series of assays. Although there are other valuable books available in this area, they do not address evaluation. Microbiological Assay for Pharmaceutical Analysis: A Rational Approach expands on the guidance given in pharmacopoeias and helps you choose the assay design most appropriate for the purpose of your assay.
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Product Details

  • ISBN-13: 9780203503973
  • Publisher: Taylor & Francis, Inc.
  • Publication date: 12/15/2003
  • Sold by: Barnes & Noble
  • Format: eBook
  • Pages: 260
  • File size: 8 MB

Table of Contents

Ch. 1 Microbiological Assay in Perspective 1
Ch. 2 The Agar Diffusion Assay - Its Quantitative Basics 9
Ch. 3 The Theory and Practice of Tube Assays for Growth-Promoting Substances 23
Ch. 4 The Theory and Practice of Tube Assays for Growth-Inhibiting Substances 37
Ch. 5 What Do We Want of an Assay? How Do We Attain Our Goal? 59
Ch. 6 General Practical Aspects of Microbiological Assays 65
Ch. 7 Standard Reference Materials 79
Ch. 8 Preliminary Evaluation of Data 89
Ch. 9 Parallel-Line Assays - Some Design and Their Evaluation 97
Ch. 10 Slope Ratio Assays - Some Designs and Their Evaluation 169
Ch. 11 Choice of Experimental Design 183
Ch. 12 Concluding Thoughts 207
Appendices 217
Index 237
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