Microfabricated Sensors: Application of Optical Technology for DNA Analysis

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2002-04-18 Hardcover New HARDCOVER, BRAND NEW COPY, Perfect Shape, MH136-308.

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This volume describes the important application of the Bio- or DNA-Chips in biomedical research such as gene expression studies and methods of construction. Details novel optical sensing and processing technologies that are being employed by researchers in this field. Specific topics include DNA Chips, detection technologies, and optical sensing and processing.
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Editorial Reviews

From The Critics
Eight contributions examine the unfolding uses of DNA- or BioChips in the fields of medical diagnostics, drug discovery, and bio/analytical chemistry. The papers are organized into sections on DNA chips, detection technologies, and optical sensing and processing. Specific topics include a system for performing gene expression profile analysis; properties, manufacturing, and applications of microarrays of gel-immobilized compounds and cells on a chip; light-powered microtransponders for high multiples level analyses of nucleic acids; and the use of digital optical chemistry for the rapid fabrication of custom oligonucleotide arrays. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780841237636
  • Publisher: American Chemical Society
  • Publication date: 4/28/2002
  • Series: ACS Symposium Series , #815
  • Pages: 170
  • Product dimensions: 6.20 (w) x 9.10 (h) x 0.70 (d)

Meet the Author

University of Cincinnati
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Table of Contents

1 Gene Expression Microarrays: A Platform for Discovery in Biological Systems 3
2 Properties, Manufacturing, and Applications of MicroArrays of Gel-Immobilized Compounds and Cells on a Chip 23
3 AlphaScreen: A Highly Sensitive, Nonradioactive and Homogeneous Assay Platform for Drug Discovery High Throughput Screening, Genomics, and Life Science Research Applications in Miniaturized Format 45
4 Light-Powered Microtransponders for High Multiplex-Level Analyses of Nucleic Acids 57
5 DNA Biosensor: Immunosensor Applications for Anti-DNA Antibody 71
6 Digital Optical Chemistry: A Novel System for the Rapid Fabrication of Custom Oligonucleotide Arrays 87
7 Low-Density Array Optical Chip Technology for the Detection of Biomolecules 107
8 Randomly-Ordered High-Density Fiber Optic Microsensor Array Sensors 129
Author Index 150
Subject Index 151
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