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Doody's Review ServiceReviewer: Daniel B. Hier, MD (University of Illinois at Chicago College of Medicine)
Description: This is an authoritative book that helps define the scope and complexity of the emerging concept of mild cognitive impairment.
Purpose: The term mild cognitive impairment or MCI is now emerging as the preferred term to define cognitive impairment that may be a prodrome to Alzheimer's disease or other dementias. This book collects authoritative reviews about the definition and use of this new terminology.
Audience: This is a key book for investigators involved in research on either early stages of dementia or prodromal states prior to the diagnosis of Alzheimer's disease. Most investigators who study dementia will want to be familiar with the concepts in this concise book.
Features: The editor and his collaborators carefully detail the history, definition, and symptomatology of minimal cognitive impairment. Two chapters examine the neuropsychological test complexities in terms of defining what is MCI and what is not. There are two excellent chapters on pathological changes in Alzheimer's disease and their relation to MCI. Two solid chapters on neuroimaging examine the overlap between MCI and Alzheimer's disease in functional and structural brain imaging. One chapter reviews the lack of biological markers for MCI. The book concludes with two very practical chapters on the office diagnosis and management of MCI.
Assessment: This is a well-written, authoritative, multiauthored book on the emerging concept of minimal cognitive impairment. Not only is it readable, but it reflects current state-of-the-art thinking about this concept that is in transition. Experts on dementia will want to have a copy of this book.