Mitochondria and Cancer / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$189.00
Used and New from Other Sellers
Used and New from Other Sellers
from $115.65
Usually ships in 1-2 business days
(Save 38%)
Other sellers (Hardcover)
  • All (9) from $115.65   
  • New (5) from $139.51   
  • Used (4) from $115.65   

Overview

Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.

Read More Show Less

Product Details

  • ISBN-13: 9780387848341
  • Publisher: Springer New York
  • Publication date: 12/2/2008
  • Edition description: 2009
  • Edition number: 1
  • Pages: 289
  • Product dimensions: 6.30 (w) x 9.30 (h) x 0.70 (d)

Table of Contents

Warburg and the Warburg hypothesis.- The marriage of genomics, proteomics and intermediary metabolism: exciting and dangerous.- Oxidative phosphorylation: the link between metabolism and cancer.- Control of glycosis and oxidative phosphorylation in fast growing tumor cells.- The role of citrate metabolism in prostate malignancy and other tumors.- The role of mihondria in the lipogenic.- Mihondrial apoptosis pathways in cancer.- Mihondrial tumor suppressors and neoplastic transformation.- Mihondrial DNA mutations and tumorigenesis.- SDHD in parganglioma.- Mihondria in hematogic maliagncies.- Mihondria and oncocytomas.- Extracellular matrix signaling by mihondria.- Mihondria as biomarkers of cancer.- Mihondria as target of cancer therapy.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)