Modern Genetic Analysis: Integrating Genes and Genomes / Edition 2

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Overview

Modern Genetic Analysis, Second Edition, the second introductory genetics textbook W.H. Freeman has published by the Griffiths author team, implements an innovative approach to teaching genetics. Rather than presenting material in historical order, Modern Genetic Analysis, Second Edition integrates molecular genetics with classical genetics. The integrated approach provides students with a concrete foundation in molecules, while simultaneously building an understanding of the more abstract elements of transmission genetics. Modern Genetic Analysis, Second Editionalso incorporates new pedagogy, improved chapter organization, enhanced art, and an appealing overall design.

The book contains predominantly color illustrations, with some black-and-white illustrations.

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Editorial Reviews

Michael Cummings
Over the years, almost all textbooks for undergraduate genetics courses have followed the historical approach, beginning with Mendel and transmission genetics, and then moving on to a discussion of molecular topics. While this is often justified as pedagogically sound, it no longer reflects the way genetics is practiced in research laboratories around the world. In addition, the historical approach artificially separates topics that can reinforce each other if the student has some background in molecular biology. The purpose is to present a modern approach to teaching genetics, using a ""DNA first"" approach. Undergraduate genetics students are the intended audience for this book. The authors have broken with tradition and written a book for a one term course in undergraduate genetics that begins with a chapter on the structure of genes and genomes, and proceeds directly to gene expression. This establishes the gene to protein to phenotype axis that serves as the backbone of this text. This approach not only gives the student insight into how geneticists think about genes, but also lays out the goals of modern genetic study: understanding the molecular basis of genetic phenomena. Mendelian genetics is not given short shrift; it is covered in a chapter that includes mitosis and meiosis, emphasizing the link between genes and chromosomes. Classical experiments in genetics are presented in a boxed section, which detracts slightly from integrating these experiments into the molecular thread of the book. This text and its pedagogy represent a new approach to teaching genetics, and the authors are to be applauded for taking this bold step. This book contains a modern synthesis ofgenetics, and instructors who take the time to master the new approach will find that the future of teaching and learning about genetics is reflected in this book.
From The Critics
Reviewer: Michael Cummings, PhD (University of Illinois at Chicago)
Description:Over the years, almost all textbooks for undergraduate genetics courses have followed the historical approach, beginning with Mendel and transmission genetics, and then moving on to a discussion of molecular topics. While this is often justified as pedagogically sound, it no longer reflects the way genetics is practiced in research laboratories around the world. In addition, the historical approach artificially separates topics that can reinforce each other if the student has some background in molecular biology.
Purpose:The purpose is to present a modern approach to teaching genetics, using a "DNA first" approach.
Audience:Undergraduate genetics students are the intended audience for this book.
Features:The authors have broken with tradition and written a book for a one term course in undergraduate genetics that begins with a chapter on the structure of genes and genomes, and proceeds directly to gene expression. This establishes the gene to protein to phenotype axis that serves as the backbone of this text. This approach not only gives the student insight into how geneticists think about genes, but also lays out the goals of modern genetic study: understanding the molecular basis of genetic phenomena. Mendelian genetics is not given short shrift; it is covered in a chapter that includes mitosis and meiosis, emphasizing the link between genes and chromosomes. Classical experiments in genetics are presented in a boxed section, which detracts slightly from integrating these experiments into the molecular thread of thebook.
Assessment:This text and its pedagogy represent a new approach to teaching genetics, and the authors are to be applauded for taking this bold step. This book contains a modern synthesis of genetics, and instructors who take the time to master the new approach will find that the future of teaching and learning about genetics is reflected in this book.

4 stars from Doody
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Product Details

  • ISBN-13: 9780716743828
  • Publisher: Freeman, W. H. & Company
  • Publication date: 2/28/2002
  • Edition description: Second Edition
  • Edition number: 2
  • Pages: 736
  • Product dimensions: 8.75 (w) x 11.12 (h) x 1.12 (d)

Table of Contents

PART 1. FUNDAMENTALS OF GENE STRUCTURE, FUNCTION, AND TRANSMISSION
1. Genetics and the Organism
2. The Structure of Genes and Genomes
3. Gene Function
4. The Transmission of DNA at Cell Division
5. The Inheritance of Single-Gene Differences
6. Genetic Recombination in Eukaryotes
7. Recombination in Bacteria and Their Viruses

PART 2 METHODS OF GENETIC MANIPULATION
8. Recombinant DNA and Genetic Engineering
9. Genomics
10. Gene Mutation: Origins and Repair Processes
11. Chromosome Mutations
12. Mutational Dissection

PART 3 SYSTEMS GENETICS: FROM GENE TO PHENOTYPE
13. Regulation of Gene Transcription
14. From Gene to Phenotype
15. Regulation of Cell Number: Normal and Cancer Cells
16. The Genetic Basis of Development

PART 4 GENETIC ANALYSIS OF POPULATIONS
17. Population Genetics
18. Quantitative Genetics
19. Evolutionary Genetics

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