Molecular Action of Insecticides on Ion Channels

Overview


Documents ongoing research into the molecular understanding of insecticide action, including the action of insecticides on major ion channel families, voltage-sensitive channels, ligand-gated channels, and biopesticide-induced channels. Presents recent advances in how researchers envision molecular binding sites of insecticides on ion channels and the molecular alterations of these sites resulting in site-insensitive resistance mechanisms. Describes new receptor-ion channels and mosaic receptor organizations as ...
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Overview


Documents ongoing research into the molecular understanding of insecticide action, including the action of insecticides on major ion channel families, voltage-sensitive channels, ligand-gated channels, and biopesticide-induced channels. Presents recent advances in how researchers envision molecular binding sites of insecticides on ion channels and the molecular alterations of these sites resulting in site-insensitive resistance mechanisms. Describes new receptor-ion channels and mosaic receptor organizations as novel sites of insecticide action.
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Product Details

  • ISBN-13: 9780841231658
  • Publisher: American Chemical Society
  • Publication date: 5/5/1995
  • Series: ACS Symposium Series , #591
  • Pages: 356
  • Product dimensions: 9.00 (w) x 6.00 (h) x 1.00 (d)

Table of Contents

Preface
1 Ion-Channel Diversity: Present and Future Roles in Insecticide Action 1
2 Sodium Channels and [gamma]-Aminobutyric Acid Activated Channels as Target Sites of Insecticides 26
3 Presynaptic Actions of Dihydropyrazoles 44
4 Insect Sodium Channel as the Target for Insect-Selective Neurotoxins from Scorpion Venom 56
5 Restriction Fragment Length Polymorphism Analysis of a Sodium-Channel Gene Locus in Susceptible and Knockdown-Resistant House Flies, Musca domestica 86
6 Actions of Insecticides on Sodium Channels: Multiple Target Sites and Site-Specific Resistance 97
7 Molecular Biological Investigations of the Property of Sodium Channels of Blattella germanica 109
8 Site-Insensitive Mechanisms in Knockdown-Resistant Strains of House Fly Larva, Musca domestica 128
9 Possible Role for Guanosine 5'-Triphosphate Binding Proteins in Pyrethroid Activity 149
10 Calcium Channel as a New Potential Target for Insecticides
11 Action of DDT and Pyrethroids on Calcium Channels in Paramecium tetraurelia 173
12 Biophysical Analysis of a Single Amino Acid Replacement in the Resistance to Dieldrin [gamma]-Aminobutyric Acid Receptor: Novel Dual Mechanism for Cyclodiene Insecticide Resistance 192
13 Structural and Functional Characterization of Insect Genes Encoding Ligand-Gated Chloride-Channel Subunits 205
14 Chloride-Channel Gene Probes from Cyclodiene-Resistant and -Susceptible Strains of Blattella germanica 216
15 Insecticide Binding Sites in the House Fly Head [gamma]-Aminobutyric Acid Gated Chloride-Channel Complex 230
16 Effects of Ivermectin on [gamma]-Aminobutyric Acid and Glutamate-Gated Chloride Conductance in Arthropod Skeletal Muscle 251
17 Ivermectin Interactions with Invertebrate Ion Channels 264
18 Resistance to Avermectins in the House Fly, Musca domestica 284
19 Permeability of Bacillus thuringiensis CryI Toxin Channels 294
20 Modulation of [delta]-Endotoxin Ion Channels 302
21 Mechanism of Action of Bacillus thuringiensis CytA and CryIVD Mosquitocidal Toxins 308
22 Identification and Functional Characterization of the Bacillus thuringiensis CryIA(c) [delta]-Endotoxin Receptor in Manduca sexta 320
23 Mode of Action of [delta]-Endotoxin from Bacillus thuringiensis var. aizawai 330
Author Index 345
Affiliation Index 345
Subject Index 346
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