Molecular and Subcellular Cardiology: Effects of Structure and Function

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Editorial Reviews

Kenneth L. Byron
This book describes the research presented at the 9th Goldberg Workshop on Molecular and Subcellular Cardiology: Effects of Structure and Function. It includes transcripts of the discussions that followed each presentation. The Henry Goldberg Workshops, an international forum of scientists and cardiologists that began in Haifa in 1984, attempt to bridge the gap between clinical cardiac medicine and molecular biology. This important and worthy objective is well met, judging by the text of this book. The book is directed toward those interested in understanding cardiac performance at the level of subcellular and molecular dynamics and, as such, is of interest to both basic scientists and clinical cardiologists. The material represents the current opinions of many highly respected cardiologists and cardiovascular research scientists. The book is a series of research papers rather than a textbook for students, with relatively few schematic illustrations and no color figures. As may be expected for a book of this type, the presentation of each chapter reflects in large part the style of the presenting authors. Many chapters contain extensive illustrations that help clarify the details of the research, and other chapters have few or no illustrations. The references are generally pertinent and up-to-date. The transcribed discussions that followed each presentation are frequently both interesting and enlightening. This book presents a current view of our understanding of molecular cardiology and provides an excellent breadth of coverage of topics related to structure and function of the heart on a micromolecular scale. It is a useful book for those who require a current overview ofmolecular cardiology while providing sufficient detail for researchers delving into specific topics in cardiovascular medicine.
Booknews
A number of basic molecular and subcellular interactions affect the activation and performance of the heart in ways of interest to cardiologists. The 32 papers from a December 1994 workshop in Haifa, Israel, make the link between basic science and clinical practice in the molecular mechanisms of sarcolemar excitability, intracellular calcium and muscle function, molecular manifestations of cell adaptation, and analysis and modeling. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: Kenneth L. Byron, PhD (Loyola University Stritch School of Medicine)
Description: This book describes the research presented at the 9th Goldberg Workshop on Molecular and Subcellular Cardiology: Effects of Structure and Function. It includes transcripts of the discussions that followed each presentation.
Purpose: The Henry Goldberg Workshops, an international forum of scientists and cardiologists that began in Haifa in 1984, attempt to bridge the gap between clinical cardiac medicine and molecular biology. This important and worthy objective is well met, judging by the text of this book.
Audience: The book is directed toward those interested in understanding cardiac performance at the level of subcellular and molecular dynamics and, as such, is of interest to both basic scientists and clinical cardiologists. The material represents the current opinions of many highly respected cardiologists and cardiovascular research scientists.
Features: The book is a series of research papers rather than a textbook for students, with relatively few schematic illustrations and no color figures. As may be expected for a book of this type, the presentation of each chapter reflects in large part the style of the presenting authors. Many chapters contain extensive illustrations that help clarify the details of the research, and other chapters have few or no illustrations. The references are generally pertinent and up-to-date. The transcribed discussions that followed each presentation are frequently both interesting and enlightening.
Assessment: This book presents a current view of our understanding of molecular cardiology and provides an excellent breadth of coverage of topics related to structure and function of the heart on a micromolecular scale. It is a useful book for those who require a current overview of molecular cardiology while providing sufficient detail for researchers delving into specific topics in cardiovascular medicine.

3 Stars from Doody
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Product Details

  • ISBN-13: 9781461357728
  • Publisher: Springer US
  • Publication date: 4/30/2013
  • Series: Advances in Experimental Medicine and Biology Series , #382
  • Edition description: Softcover reprint of the original 1st ed. 1995
  • Edition number: 1
  • Pages: 354
  • Product dimensions: 7.01 (w) x 10.00 (h) x 0.78 (d)

Table of Contents

Molecular Mechanisms of Sarcolemar Excitability: Ion Channels and Pumps in Cardiac Function; H.A. Fozzard, G. Lipkind Molecular Mechanisms of K+ Channel Blockade: 4Aminopyridine Interaction with a Cloned Cardiac Transient K+(Kv1.4) Channel; R.L. Rasmusson Integrative Models and Responses in Cardiac Ischemia; S. Horner, M.J. Lab Intracellular Calcium and Muscle Function-SR and Filaments: Sarcomere Function and Crossbridge Cycling; H.E.D.J. ter Keurs Crossbridge Dynamics in Muscle Contraction; A. Landesberg, et al. Mechanisms of the Frank-Starling Phenomena Studies in Intact Hearts; D. Burkhoff, et al. Molecular Manifestations of Cell Adaptation: Metabolic Oscillations in Heart Cells; B. O'Rourke, et al. Regulation of Adenosine Receptors in Cultured Heart Cells; D. ElAni, et al. Ventricular Remodeling in Heart Failure: The Role of Myocardial Collagen; J.S. Janicki, et al. Analysis and Modeling: From Microstructure to Macroperformance: Mechanisms of Endocardial Endothelium Modulation of Myocardial Performance; P. Mohan, et al. Vascular Gene Therapy; M.Y. Flugelman Closure: Toward Modeling the Human Physionome; J.B. Bassingthwaighte 20 additional articles. Index.

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