Molecular Basis of Cancer / Edition 1

Molecular Basis of Cancer / Edition 1

by John Mendelsohn, Peter M. Howley, Lance A. Liotta, Mark A. Israel
     
 

ISBN-10: 0721664830

ISBN-13: 9780721664835

Pub. Date: 12/28/1994

Publisher: Elsevier Health Sciences

The state-of-the-art 2nd Edition of this acclaimed reference explains the principles that form the scientific basis for our understanding of malignant transformation and the pathogenesis and treatment of cancer. Readers will find a broad update on the scientific principles of new diagnostic tests and therapeutic interventions now being used in clinical trials and

Overview

The state-of-the-art 2nd Edition of this acclaimed reference explains the principles that form the scientific basis for our understanding of malignant transformation and the pathogenesis and treatment of cancer. Readers will find a broad update on the scientific principles of new diagnostic tests and therapeutic interventions now being used in clinical trials and practice.
Incorporating the latest advances and newest research, this text also gives thorough descriptions of everything from the basic mechanisms of malignant cells and molecular abnormalities in common cancers to new approaches for Numerous examples of the latest clinical interventions help readers understand and assess the products of the biotechnology revolution. Each chapter discusses the clinical implications for treatment.

Product Details

ISBN-13:
9780721664835
Publisher:
Elsevier Health Sciences
Publication date:
12/28/1994
Edition description:
Older Edition
Pages:
573
Product dimensions:
8.66(w) x 11.02(h) x (d)

Table of Contents

Section I - Malignant Transformation
Cancer - A Genetic Disorder
Regulation of the Cell Cycle
Programmed Cell Death and Senescence
Progressive Genetic Abnormalities in Human Neoplasia
Viral Carcinogenesis
Tumor Suppressor Genes
Oncogenes and Signal Transduction
Section II - Growth and Spread of Cancer
Growth Factors and Their Receptors in Epithelial Malignancies
Metastasis and Angiogenesis: Molecular Dissection and Novel Applications
Adhesions and Mechanisms
Tumor Angiogenesis and Antiangiogenesis
Section III - Molecular Pathogenesis of Specific Malignancies
Molecular Biology of Non-Hodgkin's Lymphoma and Multiple Myeloma
Molecular Genetics of Acute Lymphoblastic Leukemia
Molecular Biology of Childhood Neoplasms
Molecular Biology of Lung Cancer
Molecular Abnormalities in Colon and Rectal Cancer
Molecular Basis of Breast Cancer
Prostate Cancer
Molecular Pathogenesis of Ovarian Cancer
Molecular Biology of Melanoma
Section IV - Molecular Basis of Cancer Therapy
Natural and Acquired Resistance to Chemotherapeutic Agents
Radiation Therapy
Monoclonal Antibodies
Interferons and Hematopoietic Cytokines
Cellular Immunity and Cytokines
Cancer-Specific Vaccines
Molecular Basis of Cancer Therapy
Molecular Markers in Cancer Therapy: Evolution of a Concept
Molecular Mechanisms of Chemoprevention and Differentiation Therapy
Counseling for Hereditary Cancer Risk

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