Molecular Biology: Academic Cell Update Edition

by David P. Clark

Overview

Molecular Biology: Academic Cell Update Edition Study Guide aims to help students get a better grasp of important concepts in Molecular Biology: Academic Cell Update. Each of the chapters in this study guide contains a summary that lets students see the bigger picture, that is, how all the techniques fit together in that chapter. A list of terms is presented in a concise format rather than spread throughout the textbook chapter to help the student remember these key terms in preparation for exams. Student can also assess their knowledge of these key terms using the Fill-in-the-Blank questions. The conceptual questions can be used for either class discussion or for independent student study. The answer key has a full explanation for the problem rather than a simple list of the answers. This study guide attempts to help the students to think about molecular biology concepts in a scientific manner, focusing each chapter on a recent research article demonstrating the concepts in the chapter. Early on in the study guide, only one or two figures of a research article are chosen so students can focus their learning on the concepts in the chapter and not on information that will be presented later in the book. In the middle of this study guide, the entire article is explained in a figure by figure basis. Then, as the student becomes more and more familiar with molecular biology techniques and the scientific method, the relevant research section contains fewer details.

Product Details

ISBN-13:	9780123814357
Publisher:	Elsevier Science
Publication date:	01/27/2012
Sold by:	Barnes & Noble
Format:	eBook
Pages:	590
File size:	18 MB
Note:	This product may take a few minutes to download.

About the Author

David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, England. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave.

Table of Contents

IntroductionChapter 1 Basic Genetics Research Paper The American Journal of Human Genetics (2009) Gain-of-Function Mutation of KIT Ligand on Melanin Synthesis Causes Familial Progressive HyperpigmentationChapter 2 Cells and Organisms Research Paper Current Biology (2009) Two Distinct Repeat Sequences of Nup98 Nucleoporins Characterize Dual Nuclei in the Binucleated Ciliate TetrahymenaChapter 3 DNA, RNA, and Protein Research Paper Structure (2009) The Structure of the Scaffold Nucleoporin Nup120 Reveals a New and Unexpected Domain ArchitectureChapter 4 Genes, Genomes, and DNA Research Paper Trends in Microbiology (2008) Genomes and knowledge a questionable relationship?Chapter 5 Cell Division and DNA Replication Research Paper Cell (2008) Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome AssemblyChapter 6 Transcription of Genes Research Paper Current Biology (2008) 30 UTRs Are the Primary Regulators of Gene Expression in the C. elegans GermlineChapter 7 Protein Structure and Function Research Paper Molecular Cell (2008) The Structure of Fcp1, an Essential RNA Polymerase II CTD PhosphataseChapter 8 Protein Synthesis Research Paper Molecular Cell (2008) Distinct eRF3 Requirements Suggest Alternate eRF1 Conformations Mediate Peptide Release during Eukaryotic Translation TerminationChapter 9 Regulation of Transcription in Prokaryotes Research Paper Cell (2009) CarD Is an Essential Regulator of rRNA Transcription Required for Mycobacterium tuberculosis PersistenceChapter 10 Regulation of Transcription in Eukaryotes Research Paper Current Biology (2009) High Temperature-Mediated Adaptations in Plant Architecture Require the bHLH Transcription Factor PIF4Chapter 11 Regulation at the RNA level Research Paper Cell (2009) Ars2 Regulates Both miRNA- and siRNA-Dependent Silencing and Suppresses RNA Virus Infection in DrosophilaChapter 12 Processing of RNA Research Paper Molecular Cell (2008) A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding YeastChapter 13 Mutations Research Paper Molecular Cell (2009) Large-Scale Expansions of Friedreichs Ataxia GAA Repeats in YeastChapter 14 Recombination and Repair Research Paper Cell (2009) Recombination and Replication in DNA Repair of Heavily Irradiated Deinococcus radioduransChapter 15 Mobile DNA Research Paper Molecular Cell (2009) Resetting the Site: Redirecting Integration of an Insertion Sequence in a Predictable WayChapter 16 Plasmids Research Paper Trends in Microbiology (2008) Commingling regulatory systems following acquisition of virulence plasmids by Bacillus anthracisChapter 17 Viruses Research Paper Molecular Cell (2009) Cellular MicroRNA and P Bodies Modulate Host-HIV-1 InteractionsChapter 18 Bacterial Genetics Research Paper Trends in Microbiology (2008) Type III secretion systems in symbiotic adaptation of pathogenic and non-pathogenic bacteriaChapter 19 Diversity of Lower Eukaryotes Research Paper Cell (2009) RAP1 Is Essential for Silencing Telomeric Variant Surface Glycoprotein Genes in Trypanosoma bruceiChapter 20 Molecular Evolution Research Paper Cell (2008) A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput SequencingChapter 21 Nucleic Acids: Isolation, Purification, Detection, and Hybridization Research Paper The American Journal of Human Genetics (2008) Mechanisms and Consequences of Small Supernumerary Marker Chromosomes: From Barbara McClintock to Modern Genetic-Counseling IssuesChapter 22 Recombinant DNA Technology Research Paper Structure (2008) NotI Is Not BoringChapter 23 The Polymerase Chain Reaction Research Paper Immunity (2009) Identification of the Human Mature B Cell miRNomeChapter 24 Genomics and DNA Sequencing Research Paper Trends in Microbiology (2008) Ecology and genomics of Bacillus subtilisChapter 25 Analysis of Gene Expression Research Paper Current Biology (2008) Global Survey of Genomic Imprinting by Transcriptome SequencingChapter 26 The Global Analysis of Proteins Research Paper Cell (2009) Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal DegradationAnswer Key