BN.com Gift Guide

Molecular Biology in Cellular Pathology / Edition 1

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $210.98
Usually ships in 1-2 business days
(Save 37%)
Other sellers (Hardcover)
  • All (4) from $210.98   
  • New (2) from $259.94   
  • Used (2) from $210.98   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$259.94
Seller since 2008

Feedback rating:

(4532)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
New Book. Shipped from UK within 4 to 14 business days. Established seller since 2000.

Ships from: Horcott Rd, Fairford, United Kingdom

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
$307.16
Seller since 2008

Feedback rating:

(17854)

Condition: New
Brand New, Perfect Condition, Please allow 4-14 business days for delivery. 100% Money Back Guarantee, Over 1,000,000 customers served.

Ships from: Westminster, MD

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
Page 1 of 1
Showing All
Close
Sort by

Overview

The latest edition of this highly successful text, covers the major advances in the methods used in cellular and molecular pathology. In recent years, knowledge of the molecular organization of the cell has led to the development of powerful new techniques that bring greater accuracy and objectives to the diagnosis, prognosis and management of many diseases and to the study of pathological states. This book describes the latest molecular techniques available for the analysis of diseases. In particular it includes new techniques using fluorescent dyes, DNA microarrays, protein chemistry, and mass spectrometry. It also incorporates information from the Human Genome Project, and the new disciplines of genomics and proteomics, where relevant to pathology. Color plates are a new feature of this edition, illustrating the advances in fluorescence labeling of cells.

Read More Show Less

Product Details

  • ISBN-13: 9780470844755
  • Publisher: Wiley
  • Publication date: 5/23/2003
  • Edition description: Subsequent
  • Edition number: 1
  • Pages: 400
  • Product dimensions: 7.03 (w) x 9.78 (h) x 1.18 (d)

Table of Contents

Preface.

Preface to Molecular Biology in Histopathology.

List of Contributors.

Chapter 1. Blotting Techniques: Methodology and Applications (Fiona Watson and C. Simon Herrington).

1.1 Introduction.

1.2 Blotting techniques.

1.3 References.

Chapter 2. In-situ Hybridisation in Histopathology (Gerald Niedobitek and Hermann Herbst).

2.1 Introduction.

2.2 Experimental conditions.

2.3 Probes and labels.

2.4 Controls and pitfalls.

2.5 Double-labelling.

2.6 Increasing the sensitivity of ISH.

2.7 What we do in our laboratories.

2.8 Applications of ISH: examples.

2.9 Perspective.

2.10 References.

Chapter 3. DNA Flow Cytometry (M. G. Ormerod).

3.1 Introduction.

3.2 Definitions and terms.

3.3 Dye used for DNA analysis.

3.4 Sample preparation for DNA analysis.

3.5 Analysis of the DNA histogram.

3.6 Quality control.

3.7 Computer analysis of the DNA histogram.

3.8 Multiparametric measurement.

3.9 Acknowledgements.

3 .10 References.

Chapter 4. Interphase Cytogenetics (Sara A. Dyer and Jonathan J. Waters).

4.1 Introduction.

4.2 Interphase cytogenics.

4.3 Applications.

4.4 Conclusion.

4.5 References.

Chapter 5. Oncogenes (Fiona Macdonald).

5.1 Introduction.

5.2 Identification of the oncogenes.

5.3 Functions of the oncogenes.

5.4 Mechanism of oncogene activation.

5.5 Oncogenes in colorectal cancer.

5.6 Oncogenes in breast cancer.

5.7 Oncogenes in lung cancer.

5.8 Oncogenes in haematological malignancies.

5.9 Other cancers.

5.10 Conclusion.

5.11 References.

Chapter 6. Molecular and Immunological Aspects of Cell Proliferation (Karl Baumforth and John Crocker).

6.1 The cell cycle and its importance in clinical pathology.

6.2 Molecular control of the cell cycle.

6.3 Cell cycle control.

6.4 The cell cycle and cancer.

6.5 Immunocytochemical markers of proliferating cells.

6.6 References.

6.7 Further reading.

Chapter 7. Interphase Nucleolar Organiser Regions in Tumour Pathology (Massimo Derenzini, et al.).

7.1 Introduction.

7.2 The AgNORs.

7.3 NOR silver-staining.

7.4 Quantitative AgNOR analysis.

7.5 AgNORs as a parameter of the level of cell proliferation.

7.6 Application of the AgNOR technique to tumour pathology.

7.7 What future for AGNORs in tumour pathology.

7.8 References.

Chapter 8. Apoptosis and Cell Senescence (Lee B. Jordan and David J. Harrison).

8.1 Introduction.

8.2 Apoptosis.

8.3 Cell senescence.

8.4 Summary.

8.5 References.

Chapte 9. The Polymerase Chain Reaction (Timothy Diss).

9.1 Introduction.

9.2 Principles.

9.3 Analysis of products.

9.4 RT-PCR.

9.5 Quantitative PCR.

9.6 DNA and RNA extraction.

9.7 Correlation of the PCR with morphology.

9.8 Problems.

9.9 Applications.

9.10 Diagnostic applications.

9.11 Infectious diseases.

9.12 Identity.

9.13 The future.

9.14 References.

9.15 Online information.

Chapter 10. Laser Capture Microdissection: Techniques and Applications in the Molecular Analysis of the Cancer Cell (Amanda Dutton, et al.).

10.1 Introduction.

10.2 The principle of LCM.

10.3 Technical considerations.

10.4 Advantages and disadvantages of LCM.

10.5 Applications of LCM.

10.6 Future perspectives.

10.7 Acknowledgements.

10.8 References.

Chapter 11. The In-situ Polymerase Chain Reaction (John J. O'Leary, et al.).

11.1 Introduction.

11.2 Overview of the methodology.

11.3 In-cell PCR technologies.

11.4 In-cell amplification of DNA.

11.5 In-cell amplification of RNA.

11.6 References.

Chapter 12. TaqMan® Technology and Real-Time Polymerase Chain Reaction (John J. O'Leary, et al.).

12.1 Introduction.

12.2 Probe technologies.

12.3 TaqMan(r) probe and chemistry.

12.4 TaqMan(r) PCR conditions.

12.5 Interpretation of results.

12.6 Relative quantitation.

12.7 References.

Chapter 13. Gene Expression Analysis Using Microarrays (Sophie E. Wildsmith and Fiona J. Spence).

13.1 Introduction.

13.2 Microarray experiments.

13.3 Data analysis.

13.4 Recent examples of microarray applications.

13.5 Conclusions.

13.6 Acknowledgements.

13.7 References.

13.8 Further reading.

13.9 Useful websites.

Chapter 14. Comparative Genomic Hybridisation in Pathology (Marjan M. Weiss, et al.).

14.1 Introduction.

14.2 Technique.

14.3 Data analysis.

14.4 Applications.

14.5 Clinical applications.

14.6 Screening for chromosomal abnormalities in fetal and neofetal genomes.

14.7 Future perspectives.

14.8 References.

Chapter 15. DNA Sequencing and the Human Genome Project (Philip Bennett).

15.1 Introduction.

15.2 DNA sequencing: the basics.

15.3 Applications of DNA sequencing.

15.4 The Human Genome Project.

15.5 Further reading.

15.6 Useful websites.

Chapter 16. Monoclonal Antibodies: The Generation and Application of 'Tools of the Trade' Within Biomedical Science (Paul N. Nelson, et al.).

16.1 Introduction.

16.2 Antibodies and antigens.

16.3 Polyclonal antibodies.

16.4 Monoclonal antibody development.

16.5 Monoclonal antibody variants.

16.6 Monoclonal antibody applications.

16.7 Specific applications.

16.8 Therapy.

16.9 Specific applications.

16.10 Conclusions.

16.11 Acknowledgements.

16.12 References.

Chapter 17. Proteomics (Kathryn Lilley, et al.).

17.1 Introduction.

17.2 Definitions and applications.

17.3 Stages in proteome analysis.

17.4 Future directions.

17.5 References.

Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)