Molecular Biology: Principles and Practice / Edition 1

Hardcover (Print)
Rent from
(Save 67%)
Est. Return Date: 06/18/2015
Buy Used
Buy Used from
(Save 40%)
Item is in good condition but packaging may have signs of shelf wear/aging or torn packaging.
Condition: Used – Good details
Used and New from Other Sellers
Used and New from Other Sellers
from $99.00
Usually ships in 1-2 business days
(Save 56%)
Other sellers (Hardcover)
  • All (11) from $99.00   
  • New (8) from $125.00   
  • Used (3) from $99.00   


Written and illustrated with unsurpassed clarity, Molecular Biology: Principles and Practice introduces fundamental concepts while exposing students to how science is done. The authors convey the sense of joy and excitement that comes from scientific discovery, highlighting the work of researchers who have shaped—and who continue to shape—the field today.

Read More Show Less

Product Details

  • ISBN-13: 9780716779988
  • Publisher: Freeman, W. H. & Company
  • Publication date: 2/11/2011
  • Edition description: First Edition
  • Edition number: 1
  • Pages: 750
  • Sales rank: 238,495
  • Product dimensions: 8.60 (w) x 11.00 (h) x 1.30 (d)

Meet the Author

Jennifer A. Doudna grew up on the Big Island of Hawaii, where she became interested in chemistry and biochemistry during her high school years. She is currently Professor of Molecular and Cell Biology and Professor of Chemistry at the University of California, Berkeley and an Investigator of the Howard Hughes Medical Institute. She received her B.A. in biochemistry from Pomona College and her Ph.D. from Harvard University, working in the laboratory of Jack Szostak, with whom she also did postdoctoral research. She next went to the University of Colorado as a Lucille P. Markey scholar and postdoctoral fellow with Thomas Cech. Doudna has also been a Donaghue Young Investigator, a Searle scholar, and a Beckman Young Investigator, and she is a former fellow of the David and Lucile Packard Foundation. She has received numerous awards for her research on RNA and RNA-protein structure and function, including the Johnson Foundation Prize for innovative research, the National Academy of Sciences Award for initiatives in research, the Alan T. Waterman Award from the National Science Foundation, and the Eli Lilly Award in Biological Chemistry from the American Chemical Society. She is a member of the Scientific Advisory Board of the David and Lucile Packard Foundation and a Trustee of Pomona College. Doudna is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. She is also a Fellow of the American Association for the Advancement of Science.

Michael O'Donnell received his Ph.D. at the University of Michigan, where he worked under Charles Williams Jr. on electron transfer in the flavoprotein thioredoxin reductase. He performed postdoctoral work on E. coli replication with Arthur Kornberg and then on herpes simplex virus replication with I. Robert Lehman, both in the biochemistry department at Stanford University. O'Donnell then became a member of the faculty of Weill Cornell Medical College in 1986 and an investigator at the Howard Hughes Medical Institute in 1992 before moving to The Rockefeller University in 1996. O'Donnell is a member of the National Academy of Sciences.

Read More Show Less

Table of Contents

I. Foundations

1. Evolution, Science, and Molecular Biology

2. DNA: The Repository of Biological Information

3. Chemical Basis of Information Molecules

4. Protein Structure

5. Protein Function

II. Nucleic Acid Structure and Methods

6. DNA and RNA Structure

7. Studying Genes

8. Genomes, Transcriptomes, and Proteomes

9. Topology: Functional Deformations of DNA

10. Nucleosomes, Chromatin, and Chromosome Structure

III. Information Transfer

11. DNA Replication

12. DNA Mutation and Repair

13. Recombinational DNA Repair and Homologous Recombination

14. Site-Specific Recombination and Transposition

15. Transcription: DNA-Dependent Synthesis of RNA

16. RNA Processing

17. The Genetic Code

18. Protein Synthesis

IV. Regulation

19. Regulating the Flow of Information

20. The Regulation of Gene Expression in Bacteria

21. The Transcriptional Regulation of Gene Expression in Eukaryotes

22. The Posttranscriptional Regulation of Gene Expression in Eukaryotes

Appendix: Model Organisms


Solutions to Problems



Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)