Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics / Edition 3

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Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics presents a fresh approach to the study of the molecular basis of cancer. Shows how an understanding of the molecular processes underpinning cancer can be directly applied to the development of new therapeutics, giving students a clear appreciation of how the theory translates to tackling the disease, Provides a carefully structured overview of the molecular mechanisms that regulate cell growth, and relates defects in these mechanisms to the onset of cancer, so that students can clearly see the link between the two, Draws on the latest research in this dynamic field and presents it with a unique clarity, making cutting-edge science readily accessible to students.
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Editorial Reviews

From the Publisher

"Beautifully illustrated book. of the best student texts on the molecular and cellular aspects of cancer available."--Times Higher Education Supplement

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Product Details

  • ISBN-13: 9780199577170
  • Publisher: Oxford University Press
  • Publication date: 6/18/2012
  • Edition description: New Edition
  • Edition number: 3
  • Pages: 352
  • Sales rank: 407,976
  • Product dimensions: 7.40 (w) x 9.60 (h) x 0.80 (d)

Meet the Author

Dr. Lauren Pecorino is Senior Lecturer and Biochemistry Programme Leader, School of Chemical and Life Sciences, University of Greenwich, UK

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Table of Contents

1. Introduction
2. DNA and Stability: Mutations versus Repair
3. Regulation of Gene Expression
4. Growth Factor Signaling and Oncogenes
5. The Cell Cycle
6. Growth Inhibition and Tumor Suppressor Genes
7. Apoptosis
8. Stem Cells and Differentiation
9. Metastasis
10. Infections and Inflammation
11. Nutrients, Hormones, and Gene Interactions
12. The Cancer Industry: Drug Development and Clinical Trial Design
13. Cancer in the Future: Focus on Diagnostics and Immunotherapy
1. Introduction
2. DNA and stability: mutations versus repair
3. Regulation of gene expression
4. Growth factor signaling and oncogenes
5. The cell cycle
6. Growth inhibition and tumour suppressor genes
7. Apoptosis
8. Stem cells and differentiation
9. Metastasis
10. Infections and inflammation
11. Nutrients, hormones, and gene interactions
12. The cancer industry: drug development and clinical trial design
13. Cancer in the future: focus on diagnostics and immunotherapy

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