Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics / Edition 2

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics / Edition 2

by Lauren Pecorino
     
 

ISBN-10: 0199211485

ISBN-13: 9780199211487

Pub. Date: 05/06/2008

Publisher: Oxford University Press, USA

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics presents a fresh approach to the study of the molecular basis of cancer. Shows how an understanding of the molecular processes underpinning cancer can be directly applied to the development of new therapeutics, giving students a clear appreciation of how the theory translates to tackling the…  See more details below

Overview

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics presents a fresh approach to the study of the molecular basis of cancer. Shows how an understanding of the molecular processes underpinning cancer can be directly applied to the development of new therapeutics, giving students a clear appreciation of how the theory translates to tackling the disease, Provides a carefully structured overview of the molecular mechanisms that regulate cell growth, and relates defects in these mechanisms to the onset of cancer, so that students can clearly see the link between the two, Draws on the latest research in this dynamic field and presents it with a unique clarity, making cutting-edge science readily accessible to students.

Product Details

ISBN-13:
9780199211487
Publisher:
Oxford University Press, USA
Publication date:
05/06/2008
Edition description:
Older Edition
Pages:
320
Product dimensions:
7.40(w) x 9.60(h) x 0.60(d)

Table of Contents

1 Introduction 1

2 DNA structure and stability: mutations versus repair 21

3 Regulation of gene expression 47

4 Growth factor signaling and oncogenes 69

5 The cell cycle 95

6 Growth inhibition and tumor suppressor genes 113

7 Apoptosis 137

8 Stem cells and differentiation 161

9 Metastasis 185

10 Infections and inflammation 211

11 Nutrients, hormones, and gene interactions 231

12 The cancer industry: drug development and clinical trial design 259

13 Cancer in the future: focus on diagnostics and immunotherapy 275

App. 1 Cell Cycle Regulation 297

App. 2 Centers for Cancer Research 298

Glossary 302

Index 311

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